PRIMOX 10 25 MG

The Brand Name PRIMOX Has Generic Salt :: Nortriptyline 

PRIMOX  Is From Company Sun Priced :: Rs. 12.5

PRIMOX have Nortriptyline is comes under Sub class Anti Depressants of  Main Class Nervous System

Main Medicine Class:: Nervous System  Sub Medicine Class :: Anti Depressants 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Nortriptyline  TAB  Rs. 12.5  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 PRIMOX  Sun  25 MG  10 Rs. 12.5

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Sun :: PRIMOX  Nortriptyline  Nervous System Anti Depressants

Indications for Drugs ::

Depression, Nocturnal enuresis

Drug Dose ::

Oral Depression Adult: 75-100 mg/day in 3 or 4 divided doses. Max: 150 mg/day in severe depression. Child: Adolescent: 30-50 mg/day in divided doses. Elderly: 30-50 mg/day in divided doses. Nocturnal enuresis Child: 6-7 yr (20-25 kg): 10 mg; 8-11 yr (25-35kg): 10-20 mg; >11 yr (35-54 kg): 25-35 mg. All doses are given 30 minutes before bedtime and treatment should continue for not >3 mth.

Contraindication ::

Mania, recent MI, arrhythmias (particularly heart block); severe liver disease; children <6 yr. Drug Precautions ::

Elderly; hepatic or renal dysfunction; benign prostatic hypertrophy; angle closure glaucoma; phaeochromocytoma; CVS disease; epilepsy; history of bowel obstruction; withdraw gradually; monitor for suicidal tendencies during early treatment; DM; thyroid disease; psychoses (may aggravate psychotic symptoms); urinary retention. Pregnancy, lactation.

Drug Side Effects ::

Tachycardia, slows conduction and prolongation of PR interval, lowers seizure threshold, peripheral neuropathy, dry mouth, constipation, urinary hesitancy, confusion and blurred vision, nausea, sweating, tremor, rashes, hypersensitivity reactions, hypomania or mania, headache, hyponatraemia, abnormal LFT, endocrine disorders, movement disorders, taste disturbances. Potentially Fatal: Rare, blood dyscrasias.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Nortriptyline, a dibenzocycloheptadiene tricyclic antidepressant, is the primary active metabolite of amitriptyline. It increases synaptic concentration of serotonin and/or norepinephrine in the CNS by blocking the neuronal reuptake of norepinephrine and serotonin.

Drug Interactions ::

Increased risk of serotonin syndrome w/ SSRIs, SNRIs, TCAs, triptans, fentanyl, lithium, tramadol, tryptophan, buspirone. May reduce antihypertensive effect of bethanidine, guanethidine, debrisoquine, clonidine. May increase metabolism w/ barbiturates. Increased risk of arrhythmias and hypotension w/ anaesth. Increased plasma level w/ fluoxetine. Potentially Fatal: Increased risk of serotonin syndrome w/ MAOIs, linezolid and methylene blue.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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