PRINZMETAL’S VARIANT ANGINA Treatment

PRINZMETAL’S VARIANT ANGINA

This is a syndrome of ischemic pain at rest and with ECG showing transient ST elevation.

  • This sydrome is caused by spasm of coronary artery leading to severe ischemia. It may occur in patients who may not have any coronary artery stenosis.
  • It is a kind of vasospastic disease like Raynaud’s phe­60menon. It may occur in young persons and smokers. Cardiac examination may be normal.
  • Coronary angiography may show transient coronary spasm close to area of coronary stenosis.

PRINZMETAL'S VARIANT ANGINA Treatment

PRINZMETAL’S VARIANT ANGINA Treatment

PRINZMETAL’S OR variant angina:

  • Chest pain that results from the spasm of coronary arteries, rather than from exertion or other increased demands on the heart.
  • On the electrocardiogram, the diagnostic hallmark is elevation of the ST segments during episodes of resting pain.
  • ECG shows ST segment elevation which reverts to normal.
  • Serum markers may be elevated or normal.
  • The pain typically occurs at rest. During coronary catheterization, the spasm is usually found near an atherosclerotic plaque, often in the right coronary artery.
  • Infusions of ergonovine may provoke it.

PRINZMETAL’S OR variant angina Treatment:

  • Nitrates,
  • calcium channel blockers,
  • sub­lingual or IV Nitrates and Prazosin.
  • Aspirin may in­crease the severity of attack.
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