PRODINE 10 2.5/5;MG

The Brand Name PRODINE Has Generic Salt :: Procyclidine 

PRODINE  Is From Company Vgr Bio. Priced :: Rs. 20.00/33.00

PRODINE have Procyclidine is comes under Sub class #N/A of  Main Class #N/A

Main Medicine Class:: #N/A  Sub Medicine Class :: #N/A 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Procyclidine  TAB  Rs. 20.00/33.00  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 PRODINE  Vgr Bio.  2.5/5;MG  10 Rs. 20.00/33.00

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Vgr Bio. :: PRODINE  Procyclidine  #N/A #N/A

Indications for Drugs ::

Parkinsonism, Drug-induced extrapyramidal syndrome

Drug Dose ::

Oral Parkinsonism and drug-induced extrapyramidal syndrome Adult: As hydrochloride: Initially, 2.5 mg tid, increased gradually by 2.5-5 mg every 2-3 days if required. Maintenance: 10-30 mg/day in 3-4 divided doses. Up to 60 mg daily may be required in some cases. Elderly: Lower doses are required. Dystonia in children Child: 7-12 yr: 1.25 mg tid; 12-18 yr: 2.5 mg tid. For emergency cases, a single dose may be given via IM or IV inj: <2 yr: 0.5-2 mg; 2-10 2-5 mg and 10-18 5-10 mg. parenteral parkinsonism drug-induced extrapyramidal syndrome adult: emergency cases: iv admin: mg, higher doses may be needed; im as a single dose, repeat after 20 minutes if needed, to max of daily. elderly: lower are required. Contraindication ::

Urinary outflow obstruction, prostatic hyperthrophy, narrow-angle glaucoma, paralytic ileus and pyloric stenosis.

Drug Precautions ::

Patients with diarrhoea. May impair a patient’s ability to perform skilled tasks e.g. driving. May precipitate psychotic episodes in patients with mental disorders. Thyrotoxicosis, heart failure, acute myocardial infarction, hypertension. Childn, elderly. Pregnancy and lactation. Avoid abrupt withdrawal.

Drug Side Effects ::

Excitability, dizziness, hallucinations (seen on abuse), dry mouth, blurred vision, constipation, urinary retention, agitation, restlessness, confusion and convulsions.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Procyclidine is a tertiary amine antimuscarinic which acts by blocking excess acetylcholine at cerebral synapses. It also exhibits direct antispasmodic effect on smooth muscle.

Drug Interactions ::

Increased plasma concentrations w/ paroxetine. Enhanced anticholinergic action w/ MAOIs and other anticholinergic drugs. Reduced therapeutic effect w/ cholinergic drugs. May antagonise the effect of parasympathomimetic agents. May reduce the absorption and therapeutic effect of sublingual or buccal nitrate tab. May reduce the efficacy of levodopa. May antagonise the GI effects of cisapride, domperidone and metoclopramide. May potentiate the vagolytic effects of quinidine. May reduce the absorption of ketoconazole.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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