PZA-CIBA 100ML 250MG/5ML

The Brand Name PZA-CIBA Has Generic Salt :: Pyrazinamide 

PZA-CIBA  Is From Company Novartis Priced :: Rs. 58

PZA-CIBA have Pyrazinamide is comes under Sub class Drugs for Tuberculosis of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Drugs for Tuberculosis 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Pyrazinamide  SYR  Rs. 58  100ML
Brand Name Company / Manufacturers Strength Unit Price / 100ML
 PZA-CIBA  Novartis  250MG/5ML  100ML Rs. 58

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Novartis :: PZA-CIBA  Pyrazinamide  Anti Infectives Drugs for Tuberculosis

Indications for Drugs ::

Tuberculosis

Drug Dose ::

Oral Tuberculosis Adult: As part of a multidrug regimen: For standard unsupervised 2-mth treatment: <50 kg: 1.5 g daily;>50 kg: 2 g daily. For intermittent supervised 2-mth treatment: <50 kg: 2 g 3 times wkly; <50 2.5 wkly. child: as part of a multidrug regimen: for standard unsupervised 2-mth treatment: 35 mg>Contraindication ::

Hypersensitivity; existing liver disease; acute gout or hyperuricaemia. Porphyria. Pregnancy and lactation.

Drug Precautions ::

Diabetes, renal failure, history of gout, children. Monitor liver function and serum uric acid regularly.

Drug Side Effects ::

Hepatotoxicity (hepatomegaly, splenomegaly and jaundice may develop and in rare case fulminating acute yellow atrophy and death). Anorexia, nausea, vomiting, arthralgia, malaise, fever, hyperuricaemia, abnormal LFT, skin rashes. Potentially Fatal: Severe liver damage, fulminant hepatitis.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Pyrazinamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug attained at the site of the infection and the susceptibility of the infecting organism. Its activity appears to partly depend on conversion of the drug to pyrazinoic acid (POA), which lowers the pH of the environment below that which is necessary for growth of Mycobacterium tuberculosis. Susceptible strains of M. tuberculosis produce pyrazinamidase, an enzyme that deaminates pyrazinamide to POA, and the in vitro susceptibility of a given strain of the organism appears to correspond to its pyrazinamidase activity.

Drug Interactions ::

0

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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