Rabeprazole

Details About Generic Salt ::  Rabeprazole 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  GERD,

7A. GERD, ULCER/ANTACIDS in 7. GASTROINTESTINAL SYSTEM
RABEPRAZOLE
PPI | ANTI-ULCER
PK: A: Well absorbed M: Hepatic E: Urine

Indications & Dose: DUODENAL ULCER PO Adult 20mg/day 4wk before breakfast | EROSIVE/ULCERATIVE GERD PO Adult 20mg OD 4-8 wk, if no response continue for 8 wk, MD 20mg OD Elderly Same as adult dose | GASTROESPHAGEAL REFLUX Symptomatic therapy PO Adult 20mg/day 4 wk, if no response continue for another 4 wk Child >12 yr: 20mg/day 8 wk | GI HYPERSECRETORY CONDITIONS PO Adult 60mg OD, may increase dose 100mg OD/60mg BID | H.PYLORI INFECT Combination therapy PO Adult 20mg BID 1 wk for 7 days with clarithromycin (500mg BID) & amoxicillin (1g)

Contra: Hypersensitivity

Precautions: Hepatic/renal impairment, GI infection, osteoporosis

ADR: Others: headache, constipation, flatulence, nausea, vomiting, diarrhea, dizziness

DDI: Serious Ketoconazole bioavailability reduces, Warfarin increases INR & PT, Digoxin level increases, Atazanavir reduces drug level

Diet: Without food

Monitor: Symptomatic response

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