REPA 10 0.5MG

The Brand Name REPA Has Generic Salt :: Repaglinide 

REPA  Is From Company Mano Ph. Priced :: Rs. 19.9

REPA have Repaglinide is comes under Sub class Insulin , Anti Diabetic drugs of  Main Class Endocrine,Steroid Hormones , Metabolic System

Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System  Sub Medicine Class :: Insulin , Anti Diabetic drugs 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Repaglinide  TAB  Rs. 19.9  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 REPA  Mano Ph.  0.5MG  10 Rs. 19.9

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Mano Ph. :: REPA  Repaglinide  Endocrine,Steroid Hormones , Metabolic System Insulin , Anti Diabetic drugs

Indications for Drugs ::

Type 2 DM

Drug Dose ::

Adult: PO Initial: 0.5 mg before main meals. May adjust dose 1-2 wkly, up to 4 mg/dose. Max: 16 mg/day.

Contraindication ::

Diabetic ketoacidosis; severe hepatic impairment, type 1 diabetes; hypersensitivity. Lactation.

Drug Precautions ::

Myocardial infarction, coma, trauma during surgery, elderly, malnourished and debilitated patients. Hepatic or severe renal impairment. Pregnancy.

Drug Side Effects ::

Hypoglycaemia, nausea, diarrhoea, constipation, vomiting, dyspepsia, arthralgia, sinusitis, rhinitis, back pain; rash, pruritus, urticaria; visual disturbances.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Repaglinide stimulates release of insulin from pancreatic ?-cells by inhibiting K efflux via closure of ATP regulated K channels. This results in depolarization of the cell and opening of voltage-dependent Ca channels, which increases influx of Ca into the beta cells and causes release of insulin.

Drug Interactions ::

Cytochrome P450 3A4 inducers eg. rifampicin, barbiturates and carbamazepine may increase repaglinide metabolism. NSAIDs and other highly protein bound drugs eg, salicylates, sulphonamides, phenylbutazone, oral anticoagulants and hydantoins may potentiate action of repaglinide. Ketoconazole, fluconazole, itraconazole and erythromycin may increase plasma conc of repaglinide. Antagonistic effect with drugs causing hyperglycaemia. Concurrent use with gemfibrozil may lead to enhanced and prolonged blood glucose lowering effect. Potentially Fatal: Increased risk of myocardial infarction when used with isophane insulin.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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