RETRONEL 10 250MG

The Brand Name RETRONEL Has Generic Salt :: Nelfinavir 

RETRONEL  Is From Company Cytomed(Alkem) Priced :: Rs. N.I.

RETRONEL have Nelfinavir is comes under Sub class Anti Retrovirals (Drugs for HIV) of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Anti Retrovirals (Drugs for HIV) 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Nelfinavir  TAB  Rs. N.I.  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 RETRONEL  Cytomed(Alkem)  250MG  10 Rs. N.I.

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Cytomed(Alkem) :: RETRONEL  Nelfinavir  Anti Infectives Anti Retrovirals (Drugs for HIV)

Indications for Drugs ::

HIV infection

Drug Dose ::

Oral HIV infection Adult: Combined with other antiretrovirals: 1.25 g bid or 0.75 g tid. Child: Combined with other antiretrovirals: 2-13 yr: 45-55 mg/kg bid or 25-35 mg/kg tid. Max: 0.75 g tid. Max Dosage: Child: 0.75 g tid. Hepatic impairment: Dose reduction may be required.

Contraindication ::

Hypersensitivity; lactation.

Drug Precautions ::

Pregnancy. Hepatic and renal impairment; haemophilia A or B; diabetes. Monitor for signs of lipodystrophy.

Drug Side Effects ::

Hyperglycaemia, dyslipidaemia and redistribution of body fat (protease paunch, buffalo hump, facial atrophy and heart engorgement); hypertriglyceridaemia, hypercholesterolaemia. Diarrhoea, rash, nausea, flatulence, decreased lymphocytes, decreased neutrophils, decreased haemoglobin, increased creatine kinase, increased transaminases.

Pregnancy category ::
Pregnancy category

2

Drug Mode of Action ::  

Nelfinavir is a selective, competitive, reversible HIV protease inhibitor. It inhibits HIV-1 protease preventing the cleavage of the gag-pol polyprotein resulting in the production of noninfectious virus.

Drug Interactions ::

Reduced levels/effects with antacids, phenobarbital, carbamazepine, aminoglutethimide, phenytoin, rifampicin, nafcillin, nevirapine, omeprazole, nevirapine. Increased serum levels/effects with azole antifungal agents, cimetidine, efavirenz. Increased serum levels/effects of azithromycin, calcium channel blockers, clarithromycin, corticosteroids (e.g. fluticasone), mirtazapine, nateglinide, nefazodone, ciclosporin, sirolimus, tacrolimus, venlafaxine, eplerinone, fentanyl, atorvastatin, phosphodiesterase-5 (PDE-5) inhibitors, rifabutin, trazodone, TCAs. Reduced serum levels/effects of hormonal contraceptives, methadone, theophylline derivatives. Potentially Fatal: Increased serum levels/toxicity of amiodarone, cisapride, pimozide, midazolam, triazolam, ergot alkaloids, lovastatin, simvastatin, quinidine.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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