Ritodrine

Details About Generic Salt ::  Ritodrine 

Main Medicine Class:: Reproductive System   Sub Medicine Class ::  Tocolytics

11D. TOCOLYTICS in 11. REPRODUCTIVE SYSTEM
RITODRINE
SYMPATHOMIMETIC | UTERINE RELAXANT
PK: A: Rapid M: Hepatic E: Urine

Indications & Dose: PRETERM LABOR IV Adult Inf: Initially 50µg/min increased by 50µg/min every 10min till therapeutic response is achieved, max rate 150-350µg/min. Continue inf for 12-48h after the contractions have stopped. Administer 10mg PO q2h for 24h 30min before the end of IV inf followed by 10-20mg q4-6 h according to patient’s response max 120 mg/day

Contra: Hypersensitivity, tachyarrhythmias, eclampsia & severe pre-eclampsia, IHD

Precautions: Pulmonary edema, severe asthma, DM, glaucoma, hyperthyroidism, hypokalemia, seizures, Susceptibility to QT-interval prolongation, HTN, CVD

ADR: Serious: leucopenia /agranulocytosis, tremor, palpitations, tachycardia, nervous tension, peripheral vasodilatation, hypokalemia, MI, hypersensitivity, RTI, Others: nausea/vomiting, dizziness, drowsiness, vertigo, headache

DDI: Serious Corticosteroids/Amphotericin-B/Loop diuretics/Thiazides causes hypokalemia, Glycopyrrolate causes SVT, Atropine causes tachycardia, Cyclopropane leads to HTN

Diet:

Monitor: Maternal pulse, state of hydration

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