Salmeterol

Details About Generic Salt ::  Salmeterol 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Drugs For Asthma,COPD,ARDS

6A. DRUGS FOR ASTHMA/COPD/ARDS in 6. RESPIRATORY SYSTEM
SALMETEROL
ß2-ADRENERGIC AGONIST (LONG-ACTING) | BRONCHODILATOR
PK: A: Variable M: Hepatic E: Feces & urine

Indications & Dose: ASTHMA Inh Adult 50µg (1 inh) q12h Child >4 yr: Same as adult dose50µg/inhalation | CHRONIC OBSTRUCTIVE PULMONARY DISEASE Maintenance therapy Inh Adult 50µg(1 inh) q12h50µg/inhalation | EXERCISE-INDUCED ASTHMA Inh Adult 50µg (1 inh) at least 30min before exercise Child >4 yr: Same as adult dose50µg/inhalation

Contra: hypersensitivity, as monotherapy in asthma, status asthmaticus, acute episodes of asthma/COPD

Precautions: CVD, acute episodes of COPD, hepatic impairment, hyperthyroidism, hypokalemia, seizures, glaucoma

ADR: Serious: HTN, edema, throat irritation, oropharyngeal candidiasis, immediate bronchospasm, Others: headache, dizziness, sleep disturbance, fever, anxiety, migraine, rash, urticaria, hyperglycemia, nausea, dyspepsia, nasal congestion

DDI: Serious TCAs/MAOIs increases effects of drug on vascular system, Thiazides/Loop diuretics increases hypokalemia

Monitor: FEV1, peak flow, PFTs, BP, HR

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