Silodosin

Details About Generic Salt ::  Silodosin 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

10C. DRUGS FOR PROSTATE DISORDERS in 10. GENITO-URINARY SYSTEM
SILODOSIN
ALPHA1-ADRENERGIC RECEPTOR BLOCKER | DRUG FOR BPH
PK: D: 49.5L (Vd) M: Hepatic E: Feces & urine

Indications & Dose: BENIGN PROSTATIC HYPERPLASIA PO Adult 8mg/day

Contra: Hypersensitivity, severe renal impairment, severe hepatic impairment, Concomitant strong CYP3A4 inhibitors/P-glycoprotein inhibitors

Precautions: mild-to-moderate hepatic impairment, elderly (risk of hypotension), women/children, concomitant use of antihypertensives

ADR: Serious: Retrograde ejaculation, Others: Diarrhea, headache, insomnia, dizziness, orthostatic hypotension, nasopharyngitis, nasal congestion, sinusitis

DDI: Others Carbamazepine/Aspirin/Clotrimazole decrease silodosin effects, Cyclosporine/Carbidopa+Levodopa/Indinavir increase silodosin effects, Alfuzosin increases antihypertensive activity, Mefloquine increases silodosin effects leads to life threatening interaction

Diet: with food

Related Posts:
You May Also Like::