Solifenacin

Details About Generic Salt ::  Solifenacin 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

10D. DRUGS ACTING ON BLADDER in 10. GENITO-URINARY SYSTEM
SOLIFENACIN
ANTI-CHOLINERGIC | RENAL AND GENITOURINARY AGENT
PK: D: 600L (Vd) M: Hepatic E: Urine (69%) & feces (23%)

Indications & Dose: URGE URINARY INCONTINENCE/ URGENCY/URINARY FREQUENCY PO Adult 5mg OD, increase 10mg OD if needed

Contra: hypersensitivity, urinary retention, gastric retention, uncontrolled narrow-angle glaucoma

Precautions: hepatic/renal impairment, history of QT prolongation, controlled (treated) narrow-angle glaucoma, bladder outflow obstruction, children

ADR: Serious: edema, HTN, blurred vision, Others: influenza, xerostomia, constipation, headache, fatigue, UTI

DDI: Serious Ketoconazole increases drug exposure

Diet: With/without food

Monitor: Anticholinergic effects, GFR,LFTs

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