Tamsulosin

Details About Generic Salt ::  Tamsulosin 

Main Medicine Class:: Genito Urinary System   Sub Medicine Class ::  Drugs For Prostate Disorders

10C. DRUGS FOR PROSTATE DISORDERS in 10. GENITO-URINARY SYSTEM
TAMSULOSIN
ALPHA-ADRENERGIC BLOCKER | DRUG FOR BPH
PK: A: >90% D: 16L (Vd) M: Hepatic E: Uirne & feces

Indications & Dose: BENIGN PROSTATIC HYPERPLASIA Symptomatic therapy PO Adult MR: 400µg/day, may increase to 800µg/day after 2-4 wk if needed

Contra: Hypersensitivity, severe hepatic impairment

Precautions: Prostate cancer, priapism, orthostatic hypotension/syncope, intraoperative floppy iris syndrome, antihypertensives

ADR: Serious: orthostatic hypotension, ejaculation abnormalities, rhinitis, blurred vision, pharyngitis, sinusitis, libido decreased, somnolence, floppy iris syndrome, Others: dizziness, headache, malaise, diarrhea, nausea, gum pain, weakness, toothache

DDI: Serious Verapamil increases adverse effects of drug, Erythromycin/Cimetidine/Fluoxetine/Ketoconazole increases drug levels

Diet: After food (30 min)

Monitor: Vital signs

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