Details About Generic Salt ::  Timolol , Latanoprost 

Main Medicine Class:: Ocular   Sub Medicine Class ::  Anti Glaucoma Drugs

3A. ANTI-GLAUCOMA DRUGS in 3. OCULAR
TIMOLOL + LATANOPROST
ß-BLOCKER;PROSTAGLANDIN | ANTI-GLAUCOMA

Indications & Dose: INTRA-OCULAR PRESSURE TP Adult Timolol (0.5%) plus Latanoprost (0.005%): Instill 1 drop into affected eye(s) OD in patients with open-angle glaucoma & ocular HTN

Contra: hypersensitivity, COPD, history of bronchial asthma, sinus bradycardia, 2nd/3rd degree AV block, cardiogenic shock, cardiac failure, other beta blockers, sinus node dysfunction, metabolic acidosis, Prinzmetal’s angina

Precautions: avoid abrupt withdrawal, history of severe anaphylaxis to allergens, DM, Myasthenia gravis, HF, pheochromocytoma

ADR: Serious: vision abnormalities, sinusitis, bronchitis, cataract, conjuctivitis, hypercholesterolemia, HTN, chest pain, increased iris pigmentation, URTI, arthritis, retinal disorder, eyelid edema, Others: dizziness, dyspepsia, dyspnea, eyelash alterations, ocular irritation, skin rashes, headache, depression, flu like symptoms, infections

DDI: Serious NSAIDs/Barbiturates decreases drug efficacy, β-blockers effects are increased, MAOIs/CCBs Increases drug efficacy, Theophylline levels are reduced

Monitor: IOP, iris colour changes, eyelash changes, systemic effects of beta blockade

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