Trimipramine

Details About Generic Salt ::  Trimipramine 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

1D. ANTI-DEPRESSANTS in 1. NERVOUS SYSTEM
TRIMIPRAMINE
DIBENZAZEPINE TCA | ANTI-DEPRESSANT
PK: A: Rapid M: Hepatic E: Urine

Indications & Dose: DEPRESSION PO Adult 50-75mg/day, gradually increased to 150-300mg/day Elderly Initially 50mg/day, increased gradually to 100mg/day

Contra: Hypersensitivity, heart block, cardiac arrhythmias, MI, severe liver disease

Precautions: Angle-closure glaucoma, pheochromocytoma, CVD, hepatic impairment, children, elderly, history of epilepsy

ADR: Serious: tinnitus, bone-marrow depression, blood disorders, hypersensitivity reactions, orthostatic hypotension, tachycardia, angioedema, increased IOP, tremor, seizures, peripheral neuropathy, Others: dry mouth, constipation, urinary retention, blurred vision, drowsiness, urticaria, hyperthermia, headache, confusion, hallucinations, sour/metallic taste, stomatitis, nausea, vomiting, gastric irritation

DDI: Serious MAOIs causes serotonin syndrome, Fluvoxamine/Diltiazem/Quinidine/Verapamil increases drug level, SSRIs increases drug levels, Venlafaxine/Bupropion leads to seizures

Diet: With/without food

Related Posts:
You May Also Like::