Valdecoxib

Details About Generic Salt ::  Valdecoxib 

Main Medicine Class:: Musculoskeletal Disorders , Pain   Sub Medicine Class ::  Analgesics , Anti inflammatory Drugs

12E. ANALGESICS & ANTI-INFLAMMATORY DRUGS in 12. MUSCULOSKELETAL DISORDERS & PAIN
VALDECOXIB
COX-2 INHIBITOR, NSAID | ANTI-INFLAMMATORY
PK: A: Rapid D: 86 L (Vd) M: Hepatic E: Urine, feces

Indications & Dose: OSTEOARTHRITIS/RHEUMATOID ARTHRITIS PO Adult 10mg OD | PRIMARY DYSMENORRHEA PO Adult 20mg BID

Contra: Renal impairment, CABG surgery

Precautions: History of ulcer disease/GI bleeding, history of a sulfonamide allergy, elderly/debilitated patients

ADR: Serious: GI ulceration, GI bleeding & Perforation, erythema multiforme, SJS, TEN, hypersensitivity reactions, renal papillary necrosis, renal toxicity, blood disorders, aggravated HTN, ARF, pancreatitis, ALT & AST increased, cardiomyopathy, aneurysm, angina pectoris, arrhythmia, coronary artery disorder, hypotension, CHF, fluid retention, edema, cellulitis, blurred vision, Others: cataract, apnea, pleural effusion, pulmonary edema, dermatitis, constipation, dry mouth, appetite increased, confusion, depression, insomnia, nervousness, urinary incontinence, UTI, dyspepsia

Diet: With/without food

Monitor: signs & symptoms of GI bleeding, LFTs

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