Vitamin B12 (Cyanocobalamin)

Details About Generic Salt ::  Vitamin B12 (Cyanocobalamin) 

Main Medicine Class:: Vitamins   Sub Medicine Class ::  Vitamins , Minerals

20A. VITAMINS & MINERALS in 20. VITAMINS, MINERALS AND COMBINATIONS
VITAMIN B12 (CYANOCOBALAMIN)
WATER-SOLUBLE VITAMIN | SUPPLEMENT
PK: D: Extensive M: Hepatic E: Feces, urine

Indications & Dose: PERNICIOUS ANEMIA Combination therapy IM/SC Adult 100µg/day 6-7 days, if improvement, administer same dose on alternate days for 7 doses, then q3-4 days for 2-3 wk. Once hematologic values have returned to normal MD 100µg/month administer concomitantly with folic acid 1mg/day for 1 month Child 30-50µg/day for 2 or more wk, (total dose of 1000-5000µg), MD 100µg/month administer concomitantly with folic acid 1mg/day for 1 month | VITAMIN B12 DEFICIENCY IM/SC Adult Initially 30µg/day 5-10 days, MD 100-200µg/month

Contra: Hypersensitivity

Precautions: Leber’s disease

ADR: Serious: Hypersensitivity reactions, arrhythmias, Others: rhinitis, nausea, headache

DDI: Serious Hormonal Contraceptives decreases drug level, Chloramphenicol leads to attenuation of drug effects, H2RA/Colchicine/Neomycin/Omeprazole/Salicylic acid reduces drug absorption

Diet: Without food

Monitor: Vit B12 level, CBC

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