Zanamivir

Details About Generic Salt ::  Zanamivir 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

13N. ANTI-RETROVIRALS (DRUGS FOR HIV) in 13. ANTI-INFECTIVES
ZANAMIVIR
NEURAMINIDASE INHIBITOR | ANTI-VIRAL
PK: A: Poor M: None E: Urine & feces

Indications & Dose: INFLUENZA A & B Inh Adult 10mg BID 5 days starts within 48h after onset of symptoms Child 10mg BID 5 days starts within 36-48h after onset of symptoms | Prophylactic therapy Inh Adult Post-exposure prophylaxis: 10mg OD 10days starts within 36h of exposure, seasonal prophylaxis: 10mg OD 28 days & treatment starts within 5days of outbreak Child >5 yr: Post-exposure prophylaxis: Same as adult dose

Contra: Hypersensitivity, asthma/COPD

Precautions: chronic respiratory diseases

ADR: Serious: hypersensitivity, oropharyngeal edema, severe skin rashes, delirium, acute bronchospasm/decline respiratory function, arrhythmia, SJS, TEN, syncope, Others: headache, GI symptoms, cough, bronchitis, fever/chills, malaise, dizziness, anorexia, myalgia

DDI: Serious Influenza vaccines efficacy is reduced

Monitor: Abnormal behaviour

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