Zopiclone

Details About Generic Salt ::  Zopiclone 

Main Medicine Class:: Nervous System   Sub Medicine Class ::  Sedatives , Hypnotics

1A. SEDATIVES & HYPNOTICS in 1. NERVOUS SYSTEM
ZOPICLONE
NON-BENZODIAZEPINE | HYPNOTIC
PK: A: Rapid D: Extensive M: Hepatic E: Urine (5%)& feces (16%)

Indications & Dose: INSOMNIA Short-term therapy PO Adult 7.5mg HS Elderly 3.75mg HS

Contra: Hypersensitivity to drug, myasthenia gravis, respiratory failure, severe sleep apnea syndrome, long-term therapy

Precautions: Elderly, muscle weakness, history of drug abuse, psychiatric illness, hepatic/renal impairment, depression, drug abuse/alcoholism, abrupt withdrawal

ADR: Serious: Hypersensitivity reactions, sedation, depression, paradoxical excitation, respiratory depression, hypotension, disinhibition, jaundice, blood disorders, urinary retention/incontinence, visual disturbances, Others: GI disturbances, bitter or metallic taste, Headache, drowsiness, muscle weakness, ataxia, vertigo, confusion, slurred speech, libido, tremor

DDI: Others Ketoconazole/Itraconazole increases drug level, Rifampicin reduces drug level

Diet: After food (just before bedtime)

Monitor: LFTs, excessive drowsiness (in elders)

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