Article Contents ::
Details About Generic Salt :: Bisoprolol
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Anti Hypertensives
| 4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM |
| BISOPROLOL |
| ß1-ADRENERGIC BLOCKER | ANTI-HYPERTENSIVE |
| PK: A: Rapid D: Extensive M: Hepatic E: Urine (50%) & feces (<2%) |
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Indications & Dose: HYPERTENSION PO Adult 2.5-10mg/day, may be increased to 10mg max 20mg/day Elderly Initially 2.5mg/day, may be increased by 2.5-5mg/day max 20mg/day |
| Contra: Cardiogenic shock, overt cardiac failure, marked sinus bradycardia, heart block greater than first-degree, bronchospasm/asthma, COPD, metabolic acidosis, hypotension, Prinzmetal’s angina, severe peripheral arterial disease, sinus bradycardia
Precautions: first-degree heart block, during drug withdrawal, pheochromocytoma, DM, conduction abnormality, hepatic/renal impairment, Myasthenia gravis, PVD, raynaud’s disease, psoriasis, psychiatric disease, thyrotoxicosis ADR: Serious: chest pain, HF, bradycardia, orthostatic hypotension, visual disturbances, pulmonary edema, arrhythmias, ischemic colitis, pancreatitis, blood disorder, hepatomegaly, bronchospasm, Others: rash, weight gain, cold extremities, depression, dizziness, headache, malaise, fatigue, insomnia, hypoesthesia, diarrhea, vomiting, nausea, arthralgia, URTI, dyspnea DDI: Serious Theophylline causes bronchospasm in asthma patients, MAOIs causes HTN, GA causes myocardial depression, Rifampicin increases drug clearance Diet: With/without food Monitor: BP, ECG |