Article Contents ::
Details About Generic Salt :: Valdecoxib
Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Analgesics , Anti inflammatory Drugs
| 12E. ANALGESICS & ANTI-INFLAMMATORY DRUGS in 12. MUSCULOSKELETAL DISORDERS & PAIN |
| VALDECOXIB |
| COX-2 INHIBITOR, NSAID | ANTI-INFLAMMATORY |
| PK: A: Rapid D: 86 L (Vd) M: Hepatic E: Urine, feces |
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Indications & Dose: OSTEOARTHRITIS/RHEUMATOID ARTHRITIS PO Adult 10mg OD | PRIMARY DYSMENORRHEA PO Adult 20mg BID |
| Contra: Renal impairment, CABG surgery
Precautions: History of ulcer disease/GI bleeding, history of a sulfonamide allergy, elderly/debilitated patients ADR: Serious: GI ulceration, GI bleeding & Perforation, erythema multiforme, SJS, TEN, hypersensitivity reactions, renal papillary necrosis, renal toxicity, blood disorders, aggravated HTN, ARF, pancreatitis, ALT & AST increased, cardiomyopathy, aneurysm, angina pectoris, arrhythmia, coronary artery disorder, hypotension, CHF, fluid retention, edema, cellulitis, blurred vision, Others: cataract, apnea, pleural effusion, pulmonary edema, dermatitis, constipation, dry mouth, appetite increased, confusion, depression, insomnia, nervousness, urinary incontinence, UTI, dyspepsia Diet: With/without food Monitor: signs & symptoms of GI bleeding, LFTs |
