Olsalazi

Details About Generic Salt ::  Olsalazi

Main Medicine Class:: Intestinal anti-inflammatory,aminosalicylic acid derivative   

(OLE-SAL-uh-zeen SO-dee-uhm)
Dipentum
Class: Intestinal anti-inflammatory/aminosalicylic acid derivative

 

Drugs Class ::

 Action Bioconverted to 5-aminosalicylic acid (mesalamine) in colon. Although mechanism of action is unknown, it probably reduces inflammation of colon topically by preventing production of substances involved in inflammatory process such as arachidonic acid.

Indications for Drugs ::

 Indications Maintenance of remission of ulcerative colitis in patients intolerant of sulfasalazine.

Drug Dose ::

 Route/Dosage

ADULTS: PO 500 mg bid (2 capsules) (total of 1 g/day).

Contraindication ::

 Contraindications Hypersensitivity to salicylates or any product component.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Renal impairment: Patients with history of renal disease or dysfunction may have worsening of renal function.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CNS: Headache; fatigue; drowsiness; lethargy; depression. DERM: Rash; itching. GI: Diarrhea; abdominal pain, cramps; nausea; dyspepsia; bloating; anorexia. OTHER: Arthralgia; upper respiratory infection.

Drug Mode of Action ::  

 Action Bioconverted to 5-aminosalicylic acid (mesalamine) in colon. Although mechanism of action is unknown, it probably reduces inflammation of colon topically by preventing production of substances involved in inflammatory process such as arachidonic acid.

Drug Interactions ::

 Interactions None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess baseline vital signs, weight, BUN, creatinine, ALT, and AST.
  • Monitor elimination patterns, color, and consistency of stools.
  • Assess for rashes, respiratory difficulty, abdominal pain, vomiting, diarrhea, abdominal distention, or lethargy, and notify physician of any problems.

Drug Storage/Management ::

 Administration/Storage

  • Administer with meals.
  • Store at room temperature.

Drug Notes ::

 Patient/Family Education

  • Caution patient to notify physician of rashes, respiratory difficulty, lethargy, muscle weakness, vomiting, diarrhea or abdominal distention, or worsening of abdominal pain.
  • Advise patient not to take double doses if one is missed. If > 1 dose is missed, tell patient to notify physician.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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