The Brand Name FADVIC-40 Has Generic Salt :: FEBUXOSTAT 

FADVIC-40  Is From Company Emcure Priced :: Rs. 150

FADVIC-40 have FEBUXOSTAT is comes under Sub class Anti Gout Drugs of  Main Class Musculoskeletal Disorders , Pain

Main Medicine Class:: Musculoskeletal Disorders , Pain  Sub Medicine Class :: Anti Gout Drugs 

Indications for Drugs ::

Gout, Hyperuricemia

Drug Dose ::

For treatment of hyperuricemia in patients with gout, Febuxostat is recommended at 40 mg or 80 mg once daily. The recommended starting dose of Febuxostat is 40 mg once daily. For patients who do not achieve a serum uric acid (sUA) less than 6 mg per dL after 2 weeks with 40 mg, Febuxostat 80 mg is recommended. No dose adjustment is necessary when administering Febuxostat to patients with mild to moderate renal or hepatic impairment. Use in Children Safety and efficacy in children below the age of 12 years have not been studied.

Contraindication ::

Patients being treated with azathioprine, mercaptopurine, or theophylline.

Drug Precautions ::

Gout Flare: An increase in gout flares is frequently observed during initiation of anti-hyperuricemic agents, including Febustat. If a gout flare occurs during treatment, Febustat need not be discontinued. Prophylactic therapy (i.e., non-steroidal anti-inflammatory drug (NSAID) or colchicine upon initiation of treatment) may be beneficial for up to six months.

Drug Side Effects ::

The most common side effects of Febustat are liver problems, nausea, gout flares, joint pain and rash.

Pregnancy category ::

3

Drug Mode of Action ::  

Febuxostat selectively inhibits xanthine oxidase, the enzyme that catalyses the conversion of hypoxanthine to xanthine to uric acid, thereby decreasing serum concentrations of uric acid.

Drug Interactions ::

May increase plasma conc of mercaptopurine, azathioprine. Alteration of metabolism of xanthine oxidase substrate drugs (eg theophylline).