The Brand Name DORINOSA Has Generic Salt :: DORIPENEM 

DORINOSA  Is From Company Natco Ph. Priced :: Rs. 2950

DORINOSA have DORIPENEM is comes under Sub class Other Beta Lactams of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Other Beta Lactams 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
DORIPENEM  INJ  Rs. 2950  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 DORINOSA  Natco Ph.  500MG  10 Rs. 2950

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Natco Ph. :: DORINOSA  DORIPENEM  Anti Infectives Other Beta Lactams

Indications for Drugs ::

Intra-abdominal infections, Bacterial infections, Septicemia, Nosocomial pneumonia, Urinary tract infections, Pyelonephritis

Drug Dose ::

Adult: IV Complicated intra-abdominal infections; Complicated urinary tract infection; Pyelonephritis; Nosocomial pneumonia. 500 mg 8 hrly. Treatment duration: May range from 5-14 days. Renal impairment: CrCl (ml/min) 30-50 250 mg every 8 hr by IV infusion over 1 hr 11-29 250 mg every 12 hr by IV infusion over 1 hr

Contraindication ::

Hypersensitivity; anaphylactic reactions to beta-lactams.

Drug Precautions ::

May decrease serum concentration of valproic acid to below therapeutic range thus increasing risk of breakthrough seizure; consider alternative antimicrobial agents or additional anti-seizure medications if concurrent usage is necessary. Prolonged use may result in Clostridium difficile-associated diarrhoea (CDAD). May cause development of drug-resistant bacteria when used in the absence of proven or strongly suspected bacterial infection. Renal impairment. Safety and efficacy have not been established in patients <18 yr old. Drug Side Effects ::

Headache, nausea, diarrhoea, rash, phlebitis, elevated hepatic enzymes, oral candidiasis, anaemia, vulvomycotic infection, renal impairment, neutropenia, leucopenia, thrombocytopenia. Potentially Fatal: Anaphylaxis, toxic epidermal necrolysis, Stevens-Johnson Syndrome, interstitial pneumonia, seizure.

Pregnancy category ::
Pregnancy category

2

Drug Mode of Action ::  

Doripenem is a broad-spectrum carbapenem with potent in vitro antibacterial activity against aerobic and anaerobic gram-positive and gram-negative bacteria including Pseudomonas aeruginosa. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins; which in turn inhibits the final transpeptidase step of peptidoglycan synthesis in bacterial cell walls.

Drug Interactions ::

Increased plasma concentration w/ probenecid. May decrease plasma levels of valproic acid thus, increasing the risk of seizures.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

DOWNLOAD OUR ANDROID APP

One of the 1st in India.High Quality Generic Medicine Portal Android Application for Online Oreder & Information.

For More Join Our Membership and Get Additional 25% off on Meds, also get MLM Benefits to get a permanent earning source.

Join Membership How to Search Medicine
Android App

We would like to keep you updated with special notifications.