Article Contents ::
Details About Generic Salt :: Fexofenadine
Main Medicine Class:: Respiratory System Sub Medicine Class :: Anti Histamines and Nasal Decongestants
6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM |
FEXOFENADINE |
H1-BLOCKER (SECOND-GENERATION) | ANTI-ALLERGIC |
also comes under 14C. Anti-Allergics in 14. Immunology & Allergy |
PK: A: Rapid M: Intestinal mucosa & hepatic E: Feces & urine |
Indications & Dose: IDIOPATHIC URTICARIA Chronic PO Adult 60mg BID or 180 mg OD Child 6 months to <2 yr: 15mg BID, 2-11 yr: 30mg BID, >12 yr: 60mg BID or 180 mg OD Elderly 60mg OD | SEASONAL ALLERGIC RHINITIS PO Adult 60mg BID or 180 mg OD Child 2-11 yr: 30mg BID, >12 yr: 60mg BID or 180 mg OD Elderly 60mg OD |
Contra: Hypersensitivity, disintegrating tablet in children <6 yr
Precautions: Renal impairment, children <6 months, do not administer with fruit juices ADR: Others: Headache, otitis media, nausea, dyspepsia, dysmenorrhea, URTI, viral infect, drowsiness, fatigue, vomiting, dizziness, myalgia DDI: Serious Itraconazole increases drug level (wheal & flare reaction), Antacids modestly reduces drug levels, Ritonavir/Lopinavir/Verapamil raises drug levels Diet: Disintegrating tab: on empty stomach Monitor: Relief of symptoms |