Article Contents ::
Details About Generic Salt :: Ivermectin
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Anthelmintics
| 13L. ANTHELMINTICS in 13. ANTI-INFECTIVES |
| IVERMECTIN |
| AVERMECTINS DERIVATIVE (SEMISYNTHETIC) | ANTHELMINTIC |
| PK: A: Well absorbed D: 3-3.5 L/kg (Vd) M: Hepatic E: Feces, urine |
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Indications & Dose: ONCHOCERCIASIS PO Adult 150µg/kg single dose, retreatment may be required q3-12 month until asymptomatic Child >15 kg: Same as adult dose | STRONGYLOIDIASIS PO Adult 200µg/kg single dose or 2 days Child >15 kg: Same as adult dose |
| Contra: Hypersensitivity
ADR: Serious: arthralgia, myalgia, lymphadenopathy, tachycardia, Others: Ocular irritation, somnolence, raised liver enzymes, postural hypotension, mazzotti reaction, fever, headache, cough, pruritus, rash, conjunctivitis, lymphadenitis, nausea, vomiting, diarrhea DDI: Serious Levamisole/Alcohol increase drug bioavailability Diet: Empty stomach Monitor: Skin, eye microfilarial counts, periodic ophthalmologic exams, stool examinations |
