Indications & Dose: TETANUS-PRONE WOUNDS IM Adult 250IU, increased to 500IU if wound older than 24h or following burns or there is risk of heavy contamination Child Same as adult dose | TREATMENT OF TETANUS IM General 150units/kg on multiple sites

Precautions: Rh +ve patients receiving treatment for blood disorders, Rh -ve patients with anti-d antibodies in their serum, IgA deficiencies, renal impairment

ADR: Serious: hypersensitivity reactions, Others: fever, chills, facial flushing, headache, nausea, local reactions with pain & tenderness

DDI: Serious Vaccines (Live & inactivated) efficacy is affected