Article Contents ::
Details About Generic Salt :: Piroxicam
Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Analgesics , Anti inflammatory Drugs
| 12E. ANALGESICS & ANTI-INFLAMMATORY DRUGS in 12. MUSCULOSKELETAL DISORDERS & PAIN |
| PIROXICAM |
| NSAID | ANALGESIC & ANTI-INFLAMMATORY |
| PK: A: Well absorbed D: 0.12-0.14 L/kg (Vd) M: Hepatic E: Urine, feces |
|
Indications & Dose: OSTEOARTHRITIS PO Adult 20mg/day as single dose, may be increase to 30-40mg/day | RHEUMATOID ARTHRITIS PO Adult 20mg/day as single dose, may be increase to 30-40mg/day |
| Contra: Hypersensitivity, perioperative pain in setting of CABG surgery
Precautions: Asthma, patients with fluid retention/HF, history of GI bleeding/PUD, CVD, renal impairment ADR: Serious: HTN, vasculitis, arrhythmias, tachycardia, anemia, Increased bleeding time, Interstitial nephritis, nephrotic syndrome, ARF, blurred vision, tinnitus, blood dyscrasias, hepatitis, anaphylaxis, Others: Fluid retention, headache, drowsiness, dizziness, nausea, vomiting, diarrhea, constipation, abdominal pain, flatulence, dyspepsia, anorexia, proteinuria DDI: Serious β-blockers effects reduced, Lithium level increased, Coumarins raises INR & bleeding time, Colestyramine reduces drug concentration Diet: With food Monitor: Occult blood loss, Hb, hematocrit & periodic renal & hepatic function tests, periodic ophthalmologic exams with chronic use |