The Brand Name BIOVAC TYPHOID Has Generic Salt :: TYPHOID 

BIOVAC TYPHOID  Is From Company Wockhardt Priced :: Rs. 150

BIOVAC TYPHOID have TYPHOID is comes under Sub class #N/A of  Main Class #N/A

Main Medicine Class:: #N/A  Sub Medicine Class :: #N/A 

Indications for Drugs ::

Prevention of typhoid, Active immunisation against typhoid fever caused by Salmonella typhi.

Drug Dose ::

Intramuscular Active immunisation against typhoid fever caused by Salmonella typhi Adult: Initial: 0.5 ml, to be given at least 2 wk before expected exposure. Booster immunisation: Repeat dose every 3 yr if exposure continues. Child: >2 yr: Initial: 0.5 ml, to be given at least 2 wk before expected exposure. Booster immunisation: Repeat dose every 3 yr if exposure continues. Elderly: Initial: 0.5 ml, to be given at least 2 wk before expected exposure. Booster immunisation: Repeat dose every 3 yr if exposure continues.

Contraindication ::

The vaccine protects against typhoid fever caused by Salmonella typhi. Protection is not conferred against paratyphoid fever or illness caused by non-invasive Salmonella. Typhoid vaccine should not be administered to subjects with known hypersensitivity to any component of the vaccine or to subjects having shown signs of hypersensitivity after previous Typhoid vaccine administration, or after any other vaccine containing Vi polysaccharide Salmonella typhi antigens. It may be expected that in patients receiving immunosuppressive treatment or patients with immunodeficiency, an adequate response may not be achieved. The administration of Typhoid vaccine should be postponed in subjects suffering from acute severe febrile illness.

Drug Precautions ::

Not for treatment of typhoid fever. Vaccination may not provide full proetction thus, travellers should be advised to take all necessary precautions to avoid contact or ingestion of potentially contaminated food or water sources. IM admin: Caution when used in patients with a history of bleeding disorders, patients on anticoagulant treatment or severely immunocompromised patients. Pregnancy, lactation.

Drug Side Effects ::

Most recepients of Typhoid vaccine experience some reactions upon vaccination. These are generally moderate and short in duration. They mainly consist of local reactions at the injection site (erythema, induration and tenderness). Systemic reactions (malaise, headache, diarrhea, vomiting, myalgia and elevated temperature) are reported less commonly. In very rare cases allergic type reactions (pruritus, rash, urticaria) may be observed.

Pregnancy category ::

3

Drug Mode of Action ::  

Live attenuateTY21a strain lacks enzyme UDP-4-galactose epimerase, which causes lipopolysaccharide to be synthesized under conditions that induce bacterial autolys; the avirulent strain produces enough lipopolysaccharide to evoke a protective immune response. Conveys active immunity via stimulation of production of endogenously produced antibodies

Drug Interactions ::

Concurrent use with antibiotics or immunoglobulins may reduce the efficacy of typhoid vaccine. Mefloquine may increase the efficacy of typhoid vaccine. May reduce the diagnostic effect of tuberculin tests. Potentially Fatal: Concurrent use with immunosuppressants may increase the adverse effects of live vaccines.