The Brand Name GR ALPHA Has Generic Salt :: Alfacalcidol
GR ALPHA Is From Company German R. Priced :: Rs. 47
GR ALPHA have Alfacalcidol is comes under Sub class Drugs affecting Bone Metabolism of Main Class Endocrine,Steroid Hormones , Metabolic System
Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System Sub Medicine Class :: Drugs affecting Bone Metabolism
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Alfacalcidol | CAP | Rs. 47 | 10 |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / 10 |
| GR ALPHA | German R. | 0.25MCG | 10 | Rs. 47 |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From German R. :: GR ALPHA | Alfacalcidol | Endocrine,Steroid Hormones , Metabolic System | Drugs affecting Bone Metabolism |
Indications for Drugs ::
Hypoparathyroidism, Hypocalcaemia, Renal osteodystrophy, Hypophosphataemia, Rickets or osteomalacia
Drug Dose ::
Adult: PO Hypocalcaemia; Hypoparathyroidism; Hypophosphataemia; Renal osteodystrophy; Rickets or osteomalacia Initial: 1 mcg/day. Maintenance: 0.25-1 mcg/day. Child: Premature infants and neonates: 0.05-0.1 mcg/kg daily; <20 kg: 0.05 mcg/kg daily. Elderly: 0.5 mcg daily. Contraindication ::
Hypercalcaemia, metastatic calcification, hyperphosphataemia (except when occurring with hypoparathyroidism), hypermagnesaemia.
Drug Precautions ::
Pregnancy, lactation, renal impairment, infants, elderly. Monitor serum levels of calcium in patients with renal failure. Caution in hypercalciuria esp in those with history of renal calculi. Avoid in patients with hypersensitivity to inj. containing propylene glycol.
Drug Side Effects ::
Anorexia, nausea, vomiting, diarrhoea, lassitude, polyuria, sweating, headache, thirst, vertigo, pruritus, rash, urticaria. Hypercalcaemia, hypercalciuria and ectopic calcification. In case of renal impairment, hyperphosphataemia. In hypercalcaemic dialysis patients, possibility of calcium influx from the dialysate should be considered.
Pregnancy category ::
0
Drug Mode of Action ::
Alfacalcidol is a precursor of the active calcitriol. It does not require renal hydroxylation but requires 25-hydroxylation in the liver for conversion to calcitriol.
Drug Interactions ::
Thiazides may increase the risk of hypercalcaemia. Some antiepileptics e.g. carbamazepine, phenobarbital, phenytoin and primidone may increase vitamin D requirements. Rifampicin, isoniazid and corticosteroids may reduce the efficacy of vitamin D.