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MS COOL DSR

The Brand Name MS COOL DSR® Has Generic Salt :: Rabeprazole,domperidone 

MS COOL DSR®  Is From Company MedicScience Life Care Pvt.Ltd Priced :: Rs. 60

MS COOL DSR® have Rabeprazole,domperidone is comes under Sub class GERD, of  Main Class Gastrointestinal System

MS COOL® DSR Rabeprazole + Domperidone DSR

MS COOL® DSR Rabeprazole + Domperidone DSR

Main Medicine Class:: Gastrointestinal System  Sub Medicine Class :: GERD, 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Rabeprazole,domperidone  TAB  Rs. 60  10
Brand Name Company / Manufacturers Strength Unit Price / 100
MS COOL DSR® MedicScience Life Care Pvt.Ltd  20,30;MG  10 Rs. 60

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From MedicScience Life Care Pvt.Ltd :: MS COOL DSR®  Rabeprazole,domperidone  Gastrointestinal System GERD,

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

Pantoprazole , Domperidone

Details About Generic Salt ::  Pantoprazole , Domperidone 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  GERD,

7A. GERD, ULCER/ANTACIDS in 7. GASTROINTESTINAL SYSTEM
PANTOPRAZOLE + DOMPERIDONE
PPI, DOPAMINE ANTAGONIST | ANTI-ULCER

Indications & Dose: DYSPEPSIA PO Adult Each tablet/capsule contains pantoprazole 40mg & domperidone 10mg: 1 tablet/capsule OD | GASTROESOPHAGEAL REFLUX DISEASE PO Adult Each tablet/capsule contains pantoprazole 40mg & domperidone 10mg: 1 tablet/capsule OD

Contra: Hypersensitivity, children <12 yr, prolonged use

Precautions: History of liver disease/GI disorder, allergy

ADR: Others: Dizziness, headache, diarrhea, rash, swelling

Cisapride

Details About Generic Salt ::  Cisapride 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  GERD,

7A. GERD, ULCER/ANTACIDS in 7. GASTROINTESTINAL SYSTEM
CISAPRIDE
SUBSTITUTED BENZAMIDE | PROKINETIC DRUG
PK: A: Rapid M: Hepatic E: Urine, feces

Indications & Dose: GASTROOESOPHAGEAL REFLUX DISEASE PO Adult 5-10mg TID-QID, max 40mg/day Child 200µg/kg TID-QID, max 800µg/kg Elderly half the usual doseassociated with decreased gastric motility & in non-ulcer dyspepsia

Contra: CYP450 potent inhibitors, drugs which prolongs QT interval or family history of QT interval prolongation, history of ventricular arrhythmia or torsade de pointes, renal failure, respiratory failure, infants <3 months after birth

Precautions: Renal/hepatic impairment, uncorrected electrolyte disturbances

ADR: Serious: Hypersensitivity reactions, arrhythmia, ventricular tachycardia, ventricular fibrillation, torsade de pointes, QT interval prolongation, extrapyramidal effects, bronchospasm, convulsions, Others: increased urinary frequency, GI disturbances, abdominal cramps, diarrhea, headache & lightheadedness, rash, pruritus

DDI: Serious Clarithromycin/Cimetidine/Diltiazem/Erythromycin/Ketoconazole/Nefazodone increases drug level leads to increase risk of QT prolongation & life-threatening ventricular arrhythmias, Ciclosporin level increased, Alcohol levels are modestly increased

Diet: 15-30min before food & at bedtime

Monitor: ECG, serum electrolytes & renal function before & during treatment

Cimetidine

Details About Generic Salt ::  Cimetidine 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  GERD,

7A. GERD, ULCER/ANTACIDS in 7. GASTROINTESTINAL SYSTEM
CIMETIDINE
H2-RECEPTOR ANTAGONIST | ANTI-ULCER
PK: A: Rapid D: 1.3L/kg (Vd) M: Hepatic E: Urine, feces

Indications & Dose: ACTIVE ULCERS Active disease Short-term therapy PO Adult 300mg QID or 800mg at HS or 400mg BID up to 8 wk | GASTRIC HYPERSECRETORY CONDITIONS PO Adult 300-600mg q6h max 2.4g/day | GASTROESOPHAGEAL REFLUX DISEASE PO Adult 400mg QID or 800mg BID 12 wk | H.PYLORI INFECT Prophylactic therapy PO Adult 400mg at HS | HEART BURN/ACID INDIGESTION/ SOUR STOMACH PO Adult 200mg BID Child >12yr: 200mg BID | PANCREATIC INSUFFICIENCY PO Adult 0.8-1.6g/day in 4 divided doses | ZOLLINGER-ELLISON SYNDROME PO Adult 300 or 400mg QID,

Contra: Hypersensitivity

Precautions: Hepatic/renal impairment, cardiovascular impairment

ADR: Others: Confusion, dizziness, drowsiness, hallucinations, agitation, psychosis, depression, anxiety, headache, diarrhea, reversible erectile dysfunction, pain at IM Inj site, gynecomastia

DDI: Serious Anti-neoplastics leads to neutropenia, agranulocytosis, Lidocaine/Benzodiazepines/Metronidazole/Phenytoin/Propranolol/TCAs/Terfenadine/Theophylline/Triamterene/Warfarin levels increases & decreases their elimination, Alcohol levels raises by drug, Magnesium Hydroxide/Aluminium hydroxide reduces drug absorption

Monitor: CBC, gastric pH, occult blood with GI bleeding, renal function

Famotidine

Details About Generic Salt ::  Famotidine 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  GERD,

7A. GERD, ULCER/ANTACIDS in 7. GASTROINTESTINAL SYSTEM
FAMOTIDINE
H2-RECEPTOR ANTAGONIST | ANTI-ULCER
PK: A: Readily but incompletely absorbed D: Infants: 0-3 months: 1.4-1.8 L/kg; >3-12 months: 2.3 L/kg; Children: 2 L/kg; Adults: 1 L/kg (Vd) M: Hepatic E: Urine

Indications & Dose: ESOPHAGITIS PO Adult 20/40mg BID 12 wk | GASTRIC ULCER PO Adult 40mg/day HS | GASTROESOPHAGEAL REFLUX DISEASE PO Adult 20mg BID 6 wk Child <3 months: 0.5mg/kg OD, 3-12 months: 0.5mg/kg BID, 1-16 yr: 1mg/kg/day in 2 divided doses, max 40mg BID | H.PYLORI INFECT PO Adult 40mg/day at HS for 4-8 wks, MD 20mg/day at HS | HYPERSECRETORY CONDITIONS PO Adult Initially 20mg q6h, may be increase in increments up to 160mg q6h | PEPTIC ULCER PO Adult Initially 20mg q6h, may be increase up to 160mg q6h Child 1-16 yr: 0.5mg/kg/day HS max 40mg/day | IV Child 1-16yr: 0.25mg/kg q12h, max 40mg/day

Contra: Hypersensitivity

Precautions: Moderate-to-severe renal impairment

ADR: Serious: Hypersensitivity reactions, Others: Headache, fatigue, dizziness, drowsiness, insomnia, pharyngitis, sinusitis, nausea, vomiting, diarrhea, constipation, abdominal pain, joint pain, pruritus, rash, fever, anorexia, gynecomastia, impotence

DDI: Serious Dipyridamole/Atazanavir absorption reduces, Cefpodoxime bioavailability reduces, Probenecid decreases drug renal clearance, Iron compounds/Interferons leads to irrelevant reduction in drug levels, Norfloxacin levels reduces, Azoles/Antacids reduces drug absorption

Diet: With/without food

Monitor: GI signs and symptoms, BUN and SeCr levels in renal impairment patients

Lansoprazole

Details About Generic Salt ::  Lansoprazole 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  GERD,

7A. GERD, ULCER/ANTACIDS in 7. GASTROINTESTINAL SYSTEM
LANSOPRAZOLE
PPI | ANTI-ULCER
PK: A: Rapid D: 14-18 L(Vd) M: Hepatic E: Feces (67%), urine (33%)

Indications & Dose: ACID-RELATED DYSPEPSIA PO Adult 15 or 30mg OD for 2-4 wk | EROSIVE ESOPHAGITIS PO Adult 30mg OD up to 8 wk Child 1-11 yr: <30 kg: 15mg OD 12 wk, >30 kg: 30mg OD 12 wk, 12-17 yr: 30mg OD 8 wk | GASTRIC ULCER PO Adult 30mg/day 8 wk | GASTROESOPHAGEAL REFLUX DISEASE PO Adult 15mg/day 8 wk Child 1-11 yr: <30 kg: 15mg OD 12 wk, >30 kg: 30mg OD 12 wk, 12-17 yr: 30mg OD 8 wk | H.PYLORI ERADICATION Combination therapy PO Adult 30mg TID with amoxicillin 1g TID 14 days or 30mg BID with amoxicillin 1g & clarithromycin 500mg BID 10-14 days | H.PYLORI INFECT Short-term therapy PO Adult 15mg OD 4 wk, MD 15mg OD | HYPERSECRETORY CONDITIONS PO Adult Initially 60mg OD, adjust dose based on patient response, doses >120mg/day given in divided doses | NON-EROSIVE ESOPHAGITIS PO Child 12-17 yr: 15mg OD 8 wk | NSAID-INDUCED GASTRIC ULCERS PO Adult 30mg OD 8 wk | Prophylactic therapy PO Adult 15mg OD 12 wk

Contra: Hypersensitivity

Precautions: Hepatic impairment, malignancy

ADR: Serious: Hypersensitivity reactions, angioedema, raised liver enzymes, Others: fever, insomnia, somnolence, agitation, depression, hallucinations, headache, confusion, anxiety, malaise, nausea, vomiting, constipation, diarrhea, abdominal pain

DDI: Serious Dipyridamole bioavailability reduces, Vecuronium duration of neuromuscular blockade increases, Methotrexate excretion reduces, Fluvoxamine inhibits drug metabolism, Levothyroxine leads to increase TSH levels by drug, Mycophenolate levels reduces, Carbamazepine levels reduces by drug, Clarithromycin/Anti-neoplastics/Digoxin/Tacrolimus levels rises, Antacids reduces drug bioavailability

Diet: Before food(breakfast)

Monitor: CBC, liver function, renal function & serum gastrin levels