Article Contents ::
- 1 The Brand Name PERIN Has Generic Salt :: Domperidone
- 2 PERIN Is From Company Dynamic Priced :: Rs. N.I.
- 3 PERIN have Domperidone is comes under Sub class Anti Emetics of Main Class Gastrointestinal System
- 4 Main Medicine Class:: Gastrointestinal System Sub Medicine Class :: Anti Emetics
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
The Brand Name PERIN Has Generic Salt :: Domperidone
PERIN Is From Company Dynamic Priced :: Rs. N.I.
PERIN have Domperidone is comes under Sub class Anti Emetics of Main Class Gastrointestinal System
Main Medicine Class:: Gastrointestinal System Sub Medicine Class :: Anti Emetics
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Domperidone | TAB | Rs. N.I. | 10 |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / 10 |
| PERIN | Dynamic | 10MG | 10 | Rs. N.I. |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From Dynamic :: PERIN | Domperidone | Gastrointestinal System | Anti Emetics |
Indications for Drugs ::
Gastritis, Lactation, Migraine, Nausea and vomiting, Gastroparesis, Non ulcer dyspepsia
Drug Dose ::
Adults : 10 – 20 mg every 4 – 8 hours daily Children : 0.2 – 0.4 mg/kg every 4 – 8 hours daily. Nausea and vomiting 10-20 mg 4-8 hrly. Max: 80 mg/day. Non ulcer dyspepsia 10-20 mg 3 times/day and at night. Migraine 20 mg 4 hrly. Max: 4 doses/24 hr. Rectal: Nausea and vomiting 60 mg twice daily.
Contraindication ::
Hypersensitivity. GI haemorrhage, obstruction and perforation, patients with prolactin releasing pituitary hormone, chronic admin or routine prophylaxis of postoperative nausea and vomiting.
Drug Precautions ::
Phaeochromocytoma; children<2 yr, elderly; renal or hepatic impairment. Risk of cardiac arrhythmias and hypokalaemia if administered IV. Pregnancy and lactation. Drug Side Effects ::
Drowsiness, extrapyramidal reactions, galactorrhoea, gynaecomastia; constipation or diarrhoea, lassitude, decreased libido, skin rash, itch. Potentially Fatal: Convulsions, arrhythmias and cardiac arrest, dysrrhythmias in patients with CV disease or hypokalaemia, patients on cancer chemotherapy. Seizures; hypertensive crisis in patients with phaeochromocytoma.
Pregnancy category ::
3
Drug Mode of Action ::
Domperidone is a peripheral dopamine-receptor blocker. It increases oesophageal peristalsis, enhances gastroduodenal coordination and lowers oesophageal sphincter pressure, gastric motility and peristalsis, thus facilitating gastric emptying and decreasing small bowel transit time.
Drug Interactions ::
May antagonise the hypoprolactinaemic effect of bromocriptine. May antagonise the prokinetic effect w/ opioid analgesics and antimuscarinics. Potentially Fatal: Potent CYP3A4 inhibitors (e.g. ketoconazole, erythromycin or ritonavir) may increase serum domperidone levels and subsequently increasing the risk of QT prolongation.
