Details About Generic Salt ::  Adapalen

Main Medicine Class:: Retinoid   

(ADE-ah-PALE-een)
Differin
Cream: 0.1%
Gel: 0.1%
Solution: 0.1%
Class: Retinoid

 

Drugs Class ::

 Action May normalize the differentiation of follicular epithelial cells, resulting in decreased microcomedone formation.

Indications for Drugs ::

 Indications Topical treatment of acne vulgaris.

Drug Dose ::

 Route/Dosage

Adults and children (12 yr and older): TOPICAL Apply a thin film once daily to affected areas after washing in the evening before bedtime.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established in children less than 12 yr. External use: Avoid contact with eyes, lips, angles of the nose, other mucous membranes, and open wounds. Irritation: May cause local irritation. May need to use less often or discontinue use. Photosensitivity: Photosensitivity may occur. Patients should minimize exposure to sunlight, including sunlamps, and use sunscreens and protective clothing over treated areas.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

DERMATOLOGIC: Erythema; scaling; dryness; pruritus, skin discomfort, burning, stinging, and irritation; sunburn; acne flares.

Drug Mode of Action ::  

 Action May normalize the differentiation of follicular epithelial cells, resulting in decreased microcomedone formation.

Drug Interactions ::

 Interactions

Potentially irritating topical products (eg, medicated or abrasive soaps and cleansers, soaps and cosmetics that have strong drying effect, products with high concentrations of alcohol, spices or limes), products containing sulfur, resorcinol, or salicylic acid: Because of increased risk of local irritation, use with caution.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess the skin and identify areas where medication is to be applied and areas that are sunburned, have cuts, eczema, or abrasions; avoid these areas.
  • Assess and document skin condition before initial application and periodically throughout treatment.
  • Monitor for side effects, including redness, scaling, dryness, or persistent itching or burning. Inform health care provider if noted and significant.
OVERDOSAGE: SIGNS & SYMPTOMS
  Redness, peeling, discomfort

Drug Storage/Management ::

 Administration/Storage

  • For topical use only. Not for ophthalmic, oral, or intravaginal use.
  • Avoid contact with eyes, lips, angles of the nose, and mucus membranes.
  • Cleanse area with a mild or soapless cleanser before applying medicated cream.
  • Cream, gel, or solution are usually applied to affected areas once daily at nighttime.
  • Apply a thin film of cream, gel, or solution to cover the affected area(s).
  • Store at controlled room temperature (68° to 77°F). Keep tube tightly capped. Keep bottle tightly capped and stored upright. Protect from freezing.

Solution

  • Apply directly to affected area(s) using supplied applicator. Replace cap after each use.

Pledgets

  • Do not use if seal is broken. Remove pledget from foil pouch just before using. Discard pledget after single use. Do not reuse pledget.

Drug Notes ::

 Patient/Family Education

  • Explain name, dose, action, and potential side effects of drug.
  • Advise patient that medication is applied topically to skin lesions once daily at nighttime.
  • Teach patient the following proper technique for applying medication: wash hands; cleanse area with mild or soapless cleanser first then apply a thin film of cream, gel, or solution to cover skin areas with acne lesions; wash hands after applying medication.
  • Inform patient that a mild sensation of warmth or slight stinging may be felt shortly after application and that this is expected and should be of no concern.
  • Warn patient that applying medication more often than prescribed or in excessive quantities will not produce more rapid improvement or better results but will result in greater side effects such as redness, scaling, and discomfort.
  • Warn patient to avoid contact with the eyes, lips, angles of the nose, and mucous membranes.
  • Advise patient to not apply to skin areas where there are cuts, abrasions, or eczema, or to sunburned skin.
  • Advise patient that moisturizers may be used but to avoid those containing alpha hydroxy or glycolic acids.
  • Advise patient that acne may appear to worsen during the first few weeks of therapy but to continue to use the cream. Improvement may not be seen for at least 2 wk but may take up to 8 wk.
  • Advise patient that local redness, drying, scaling, burning, or itching may occur during the first 2 to 4 wk of treatment and usually will lessen with continued use of medication. However, if these symptoms are bothersome or do not go away, the frequency of application may need to be reduced or the medication discontinued completely.
  • Advise patient that if severe dermal reactions occur to stop using the medication and contact the health care provider.
  • Advise patient to talk to the health care provider before using any other topical agents (eg, medicated soaps, astringents, cosmetics, or other acne products) on treated skin.
  • Advise patient to not use wax epilation on treated skin because of risk of skin erosions.
  • Warn patient to avoid unnecessary exposure to sun and sun lamps while using this medication. Advise patient to use sunscreens and protective clothing over treated areas when exposure cannot be avoided.
  • Caution patient that while using the medication, exposure to extreme weather conditions (eg, wind or cold air) may be irritating to the treated areas.
  • Advise women to contact health care provider if pregnant, planning to become pregnant, or breastfeeding.
  • Warn patient not to take any prescription or OTC drugs or dietary supplements without consulting the health care provider.
  • Advise patient that follow-up visits to examine the skin lesions may be necessary and to keep appointments.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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