Details About Generic Salt ::  Butalbi2

Main Medicine Class:: Nonnarcotic analgesic   

(BYOO-TAL-bih-tuhl/ASS-pihr-in/kaff-EEN)
Fiorinal, Fiortal, Butalbital Compound
Class: Nonnarcotic analgesic

 

Drugs Class ::

 Action Butalbital has generalized depressant effect on CNS and, in very high doses, has peripheral effects. Aspirin has analgesic, antipyretic, anti-inflammatory and antirheumatic effects; its analgesic and anti-inflammatory effects may be mediated through inhibition of prostaglandin synthetase enzyme complex. Aspirin also irreversibly inhibits platelet aggregation. Caffeine is thought to produce constriction of cerebral blood vessels.

Indications for Drugs ::

 Indications Relief of symptom complex of tension (or muscle contraction) headache.

Drug Dose ::

 Route/Dosage

ADULTS & CHILDREN ³ 12 YR: PO 1 to 2 tablets or capsules q 4 hr; maximum is 6 tablets or capsules/day.

Contraindication ::

 Contraindications Hypersensitivity to salicylates, aspirin, caffeine, or barbiturates; porphyria; bleeding disorders; syndrome of nasal polyps, angioedema and bronchospastic reactivity to aspirin or other NSAIDs; peptic ulcer.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy in children < 12 years not established. Drug dependency: Prolonged use may produce drug dependency (psychologic and physical) and tolerance. Peptic ulcer, coagulation abnormalities and preoperative states: Use with extreme caution because of increased bleeding time. Renal or hepatic impairment: Use with caution due to decreased elimination. Reye’s syndrome: May occur in children due to aspirin component; should not be used for chickenpox or flu symptoms.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CV: Tachycardia. CNS: Drowsiness; dizziness; lightheadedness; confusion; mental depression; unusual excitement; nervousness. DERM: Rash. GI: Nausea; vomiting; flatulence; heart-burn; abdominal pains; constipation.

Drug Mode of Action ::  

 Action Butalbital has generalized depressant effect on CNS and, in very high doses, has peripheral effects. Aspirin has analgesic, antipyretic, anti-inflammatory and antirheumatic effects; its analgesic and anti-inflammatory effects may be mediated through inhibition of prostaglandin synthetase enzyme complex. Aspirin also irreversibly inhibits platelet aggregation. Caffeine is thought to produce constriction of cerebral blood vessels.

Drug Interactions ::

 Interactions

Beta-blockers (eg, propranolol), doxycycline, estrogens (including oral contraceptives), felodipine, griseofulvin, nifedipine, phenylbutazone, quinidine, theophylline: Effects of these drugs may be increased. Corticosteroids: May enhance renal clearance of aspirin; sudden discontinuation of corticosteroids may result in symptoms of salicylism; effects of corticosteroids may be decreased. Insulin, oral antidiabetic agents: Hypoglycemic effects may be increased. MAO inhibitors: May increase CNS effects. Methotrexate, 6-mercaptopurine: Bone marrow toxicity may occur. NSAIDs: Increased GI ulceration or bleeding may occur. Other CNS depressants (ethanol, narcotics, general anesthetics, tranquilizers, sedative-hypnotics): Increased drowsiness, dizziness and other CNS depressive effects may occur. Sulfinpyrazone, probenecid: Uricosuric effects may be decreased. Tricyclic antidepressants: Antidepressant levels/effect may decrease. Warfarin: Anticoagulant effects may be increased or decreased.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess pain prior to administration to establish baseline.
  • Take vital signs prior to administration.
  • Assess related factors that may precipitate or worsen pain such as anxiety, fear, or stress.
  • Administer scheduled dose before pain is severe.
  • Record degree and duration of pain relief. Notify physician if product is ineffective.
  • Assess therapeutic effectiveness 1 hr after dose based on patient report of relief. Do not rely on objective signs.
  • Reassess vital signs.
  • Assess for dizziness, sedation, or euphoria.
  • Institute safety precautions if drowsiness or sedation occurs.
  • Use adjunct pain relief measures (eg, massage, positioning, maintaining quiet environment and emotional support) to enhance effectiveness.

OVERDOSAGE: SIGNS & SYMPTOMS
  Hyperthermia, tachycardia, respiratory depression, bleeding, drowsiness, confusion, coma, hypotension, hypovolemic shock, nausea, vomiting, tremor, tinnitus, fluid and electrolyte abnormalities, insomnia, restlessness

Drug Storage/Management ::

 Administration/Storage

  • Give with food or water.
  • Discard if strong vinegar-like odor is present.
  • Store in airtight, light-resistant container at room temperature.

Drug Notes ::

 Patient/Family Education

  • Caution patient that dependency/tolerance may result from long-term use.
  • Tell patient to take with food or full glass of water.
  • Instruct patient not to discontinue abruptly after long-term regular use.
  • Caution patient to avoid intake of alcoholic beverages and other CNS depressants without physician approval.
  • Warn patient to avoid any hazardous activity (eg, driving, smoking) if dizziness, drowsiness or decrease in mental acuity occurs.
  • Instruct patient to avoid sudden position changes to avoid orthostatic hypotension.
  • Advise patient to notify physician if any surgical procedures are required. Aspirin therapy should be discontinued 5 days prior to surgery to reduce potential for bleeding problems.
  • Instruct patient not to take otc medications without consulting physician.
  • Advise patient to report these symptoms to physician: Persistent or recurrent pain before next scheduled dose, difficulty breathing, buzzing in ears, increased drowsiness, vomiting, abdominal pain, tarry stools, unusual bruising or bleeding.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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