Details About Generic Salt ::  Clemasti

Main Medicine Class::    

(KLEM-ass-teen FEW-muh-rate)

Dayhist-1

Tablets

1.34 mg as fumarate (equiv. to 1 mg clemastine)

Tavist Allergy

Tablets

1.34 mg as fumarate (equiv. to 1 mg clemastine)

Clemastine Fumarate

Tablets

2.68 mg (equiv. to 2 mg clemastine)

Syrup

0.67 mg/5 mL (equiv. to 0.5 mg clemastine)

Tavist, Tavist-1

Class: Antihistamine, Ethanolamine

 

Drugs Class ::

 Action Competitively antagonizes histamine at H₁ receptor sites.

Indications for Drugs ::

 Indications Relief of symptoms associated with allergic rhinitis or other upper respiratiry allergies, such as sneezing, rhinorrhea, pruritus, and lacrimation; relief of mild, uncomplicated allergic skin manifestation of urticaria and angioedema.

Drug Dose ::

 Route/Dosage

Adults and Children over 12 yr: PO 1.34 mg bid to 2.68 mg tid (max, 8.04 mg/day).

Children 6 to 12 yr: PO (syrup only) 0.67 to 1.34 mg bid (max, 4.02 mg/day).

Contraindication ::

 Contraindications Hypersensitivity to antihistamines; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO inhibitor therapy; use in newborn or premature infants and in nursing women.

Drug Precautions ::

 Precautions

Pregnancy: Category B. Lactation: Contraindicated in nursing mothers. Children: Safety and efficacy in children less than 12 yr not established. Elderly: Elderly and debilitated patients are at an increased risk of dizziness, excessive sedation, syncope, toxic confusional states, and hypotension. Dosage reduction may be required. Special risk patients: Use drug with caution in patients predisposed to urinary retention, history of bronchial asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension. Avoid use in patients with history of sleep apnea. Hepatic impairment: Use with caution in patients with cirrhosis or other liver disorders.

PATIENT CARE CONSIDERATIONS

Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Orthostatic hypotension; palpitations; bradycardia; tachycardia; arrhythmias. CNS: Drowsiness (often transient); sedation; dizziness; faintness; disturbed coordination.EENT: Blurred vision; tinnitus. GI: Epigastric distress; nausea; vomiting; diarrhea; constipation. HEMATOLOGIC: Hemolytic anemia; thrombocytopenia; agranulocytosis. METABOLIC: Increased appetite; weight gain. RESPIRATORY: Thickening of bronchial secretions; chest tightness; wheezing; nasal stuffiness; dry mouth, nose and throat; sore throat; respiratory depression. OTHER: Hypersensitivity reactions; photosensitivity.

Drug Mode of Action ::  

 Action Competitively antagonizes histamine at H₁ receptor sites.

Drug Interactions ::

 Interactions

Alcohol, CNS depressants: May cause additive CNS depressant effects.

MAO Inhibitors: May increase anticholinergic effects of clemastine fumarate.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies, especially to antihistamines.
• Determine whether there is history of glaucoma, ulcer, asthma, or urinary tract obstruction.
• Notify health care provider if patient has history of hypertension or other cardiovascular disorders or is taking an MAO inhibitor.

OVERDOSAGE: SIGNS & SYMPTOMS   CNS depression, hallucinations, convulsions, cardiovascular collapse

Drug Storage/Management ::

 Administration/Storage

• Administer drug whole. If patient cannot take whole tablet, administer syrup form.
• Administer drug with food to avoid GI irritation.
• Store at room temperature.

Drug Notes ::

 Patient/Family Education

• Instruct patient not to take drug for 4 days before allergy testing.
• Caution elderly patients that signs of CNS depression will be more pronounced.
• Instruct patient to report the following symptoms to health care provider: difficulty breathing or problems voiding.
• Advise patient to take sips of water frequently, suck on ice chips or sugarless hard candy, or chew sugarless gum if dry mouth occurs.
• Instruct patient to avoid intake of alcoholic beverages or other CNS depressants.
• Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.
• Caution patient to avoid exposure to sunlight and to use sunscreen or wear protective clothing to avoid photosensitivity reaction.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.