Details About Generic Salt ::  Clomiphe

Main Medicine Class:: Ovulation stimulant   

(KLOE-mih-feen SIH-trate)
Clomid, Milophene, Serophene
Class: Ovulation stimulant

 

Drugs Class ::

 Action Induces ovulation in selected anovulatory women.

Indications for Drugs ::

 Indications Treatment of ovulatory failure in women desiring pregnancy when partner is fertile and potent. Unlabeled use(s): Treatment of male infertility.

Drug Dose ::

 Route/Dosage

INITIAL THERAPY PO 50 mg/day for 5 days. SECOND AND THIRD COURSES PO 100 mg/day for 5 days.

Contraindication ::

 Contraindications Liver disease; history of liver dysfunction; abnormal bleeding of undetermined origin; pregnancy.

Drug Precautions ::

 Precautions

Pregnancy: Category X. Lactation: Undetermined. Multiple pregnancy: May increase chance for multiple pregnancies. Ophthalmologic effects: May cause blurring of vision.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CV: Vasomotor flushes. CNS: Headache, dizziness; lightheadedness. EENT: Visual symptoms; blurring spots or flashes; diplopia; photophobia. GI: Abdominal pain/discomfort; distension; bloating; nausea; vomiting. HEPA: Sulfobromophthalein retention. GU: Abnormal uterine bleeding; abnormal ovarian enlargement, luteal cyst formation. OTHER: Breast tenderness.

Drug Mode of Action ::  

 Action Induces ovulation in selected anovulatory women.

Drug Interactions ::

 Interactions None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Monitor liver function tests before beginning therapy and throughout therapy in patients at risk for hepatotoxicity.
  • Notify physician if patient experiences abdominal pain, abnormal uterine bleeding, visual changes or jaundice.

Drug Storage/Management ::

 Administration/Storage

  • Administer initially over 5 days at approximately 50 mg/day. Follow with second course of 100 mg/day for 5 days.

Drug Notes ::

 Patient/Family Education

  • Caution patient that this medication must not be taken during pregnancy or when pregnancy is possible. Advise patient to use reliable form of birth control while taking this drug.
  • Counsel patient and partner in purpose of scheduling clomiphene citrate, sexual intercourse and ovulation time to be successful in achieving pregnancy.
  • Advise female patient that increased midcycle ovarian discomfort may be experienced and can assist her in planning intercourse.
  • Instruct patient of importance of well-balanced diet, mild exercise routine, and avoidance of drugs, caffeine and alcohol while attempting to achieve pregnancy.
  • Inform patient of possibility for multiple pregnancies.
  • Explain that medication may cause dizziness, hot flashes, headache, nausea and weight gain but that these effects will subside after medication is stopped.
  • Instruct patient to report these symptoms to physician: abnormal uterine bleeding, yellowish skin or eyes, blurred vision.
  • Advise patient to use caution while driving or using heavy equipment because blurring of vision can occur.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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