Details About Generic Salt ::  Flucytos

Main Medicine Class:: Anti-infective,Antifungal   

Class: Anti-infective/Antifungal


Drugs Class ::

 Action Exact mechanism is unknown; interferes with DNA and RNA synthesis. Active against Candida and Cryptococcus.

Indications for Drugs ::

 Indications Treatment of serious infections caused by susceptible strains of Candida or Cryptococcus. unlabeled use(s): Treatment of Chromomycosis.

Drug Dose ::


ADULTS & CHILDREN > 50 kg: PO 50 to 150 mg/kg/day in divided doses q 6 hr.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::


Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Bone marrow depression: Use with extreme caution in patients with bone marrow depression or those at risk (eg, hematologic disease, radiation treatment, other bone marrow suppressant drugs). Hepatic or renal impairment: Use with extreme caution in patients with renal impairment. Adjust dose according to blood levels and monitor hepatic function.


Drug Side Effects ::

 Adverse Reactions

CV: Cardiac arrest. CNS: Ataxia; hearing loss; headache; sedation; confusion; fatigue; weakness; dizziness; vertigo, paresthesia; parkinsonism; peripheral neuropathy; pyrexia; hallucinations; psychosis. DERM: Rash; pruritus; urticaria; photosensitivity. GI: Nausea; emesis; abdominal pain; diarrhea; anorexia; duodenal ulcer; GI hemorrhage. GU: Azotemia; creatinine and BUN elevation; crystalluria; renal failure; dry mouth. HEMA: Anemia; agranulocytosis; aplastic anemia; eosinophilia; leukopenia; pancytopenia; thrombocytopenia. HEPA: Hepatic dysfunction; jaundice; ulcerative colitis; increased bilirubin; elevated hepatic enzymes. META: Hypoglycemia; hypokalemia. RESP: Respiratory arrest; chest pain; dyspnea.

Drug Mode of Action ::  

 Action Exact mechanism is unknown; interferes with DNA and RNA synthesis. Active against Candida and Cryptococcus.

Drug Interactions ::


Amphotericin B: Increased therapeutic action and toxicity of flucytosine. Cytosine: Inactivates antifungal activity of flucytosine.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Ensure that baseline liver function tests, BUN, and creatinine, electrolytes, and glucose have been obtained before beginning therapy, and monitor at regular intervals.
  • Obtain baseline CBC with differential and repeat daily. Assess for bone marrow depression.
  • Obtain specimens for culture and sensitivity before beginning therapy.
  • Monitor BP at regular intervals during therapy. Assess for cardiovascular collapse.
  • Monitor blood levels of drug closely in patient with impaired renal function.
  • If patient has ataxia, hearing loss, headache, paresthesia, peripheral neuropathy, pyrexia, hallucinations, psychosis, laboratory evidence of liver or renal dysfunction, chest pain, or respiratory distress, notify physician immediately.
  Nausea, vomiting, diarrhea, CNS changes, leukopenia, thrombocytopenia, hepatitis

Drug Storage/Management ::


  • Administer capsules a few at a time over 15 min to minimize GI upset.

Drug Notes ::

 Patient/Family Education

  • Instruct patient to take capsules a few at a time over a 15-min period with food.
  • Instruct diabetic patients to monitor glucose closely.
  • Instruct patient to report the following symptoms to physician: Sore throat, cough, unusual bleeding or bruising, petechiae, blood in urine, bleeding gums, abdominal pain, nausea, vomiting, change in color or consistency of stools, fever, yellow skin/eyes, ataxia, hearing loss, paresthesia, shaking, tingling, altered sensation, parkinsonism, peripheral neuropathy, hallucinations or psychosis, anorexia, increased fatigue, rash or itching.
  • Warn patient to seek emergency care if respiratory distress or chest pain occur.
  • Advise patient that drug may cause dizziness or vertigo and to use caution while driving or performing other tasks requiring mental alertness.
  • Caution patient to avoid unnecessary exposure to sunlight and to use sunscreen and wear protective clothing to avoid photosensitivity reaction.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


One of the 1st in India.High Quality Generic Medicine Portal Android Application for Online Oreder & Information.

For More Join Our Membership and Get Additional 25% off on Meds, also get MLM Benefits to get a permanent earning source.

Join Membership How to Search Medicine
Android App

We would like to keep you updated with special notifications.