Article Contents ::

Details About Generic Salt ::  Fulvestr

Main Medicine Class:: Antiestrogen   

(fool-VESS-trant)
Faslodex
Solution for injection
50 mg/mL
Class: Antiestrogen

 Indications Treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.

 Contraindications Pregnancy; hypersensitivity to the drug or any component of the product.

 Route/Dosage

Adults: IM 250 mg into buttock at 1-mo intervals.

 Interactions

None well documented.

 Lab Test Interferences None well documented.

 Adverse Reactions

CNS: Headache; dizziness; insomnia; paresthesia; depression; anxiety. DERMATOLOGIC: Rash; sweating. EENT: Pharyngitis. GI: Nausea; vomiting; constipation; diarrhea; abdominal pain; anorexia. GU: Urinary tract infection. HEMATOLOGIC: Anemia. RESPIRATORY: Dyspnea; increased cough. OTHER: Back pain; hot flushes; bone pain; arthritis; asthenia; pain; transient pain and inflammation at injection site; vasodilation; pelvic pain; peripheral edema; chest pain; flu-like syndrome; fever; accidental injury.

 Precautions

Pregnancy: Category D. Lactation: Undetermined. Children: Safety and efficacy not established.

PATIENT CARE CONSIDERATIONS


 Administration/Storage

  • For IM administration only. Not for IV, SC, or ID administration.
  • Administer prescribed dose once monthly using prefilled syringe(s) and supplied safety needle(s).
  • Administer as single 5 mL injection or concurrent 2.5 mL injections into buttock.
  • Administer injection slowly.
  • Do not administer if cloudiness or particulate matter is noted.
  • Store prefilled syringes in refrigerator (36° to 46°C).

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies. Note history of liver function impairment, bleeding diatheses, thrombocytopenia, or concurrent use of anticoagulants.
  • Ensure that patient has negative pregnancy test before starting therapy.
  • Monitor patient for GI, CNS, general body side effects, and injection site reactions. Inform health care provider if noted and significant.

 Patient/Family Education

  • Explain name, dose, action, and potential side effects of drug.
  • Advise patient that medication will be prepared and administered by health care provider in a health care setting on a monthly basis.
  • Instruct patient to inform health care provider if any of the following symptoms occur: intolerable nausea, vomiting, constipation, diarrhea, stomach pain, headache, hot flushes, injection site pain or inflammation.
  • Instruct patient to not take any prescription or otc medications or dietary supplements unless advised by health care provider.
  • Instruct women to notify health care provider if they become pregnant, plan on becoming pregnant, or are breastfeeding.
  • Advise patient that follow-up visits and laboratory tests will be required to monitor therapy and to be sure to keep appointments.

 

Drugs Class ::

(fool-VESS-trant)
Faslodex
Solution for injection
50 mg/mL
Class: Antiestrogen

Indications for Drugs ::

 Indications Treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.

Drug Dose ::

 Route/Dosage

Adults: IM 250 mg into buttock at 1-mo intervals.

Contraindication ::

 Contraindications Pregnancy; hypersensitivity to the drug or any component of the product.

Drug Precautions ::

 Precautions

Pregnancy: Category D. Lactation: Undetermined. Children: Safety and efficacy not established.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CNS: Headache; dizziness; insomnia; paresthesia; depression; anxiety. DERMATOLOGIC: Rash; sweating. EENT: Pharyngitis. GI: Nausea; vomiting; constipation; diarrhea; abdominal pain; anorexia. GU: Urinary tract infection. HEMATOLOGIC: Anemia. RESPIRATORY: Dyspnea; increased cough. OTHER: Back pain; hot flushes; bone pain; arthritis; asthenia; pain; transient pain and inflammation at injection site; vasodilation; pelvic pain; peripheral edema; chest pain; flu-like syndrome; fever; accidental injury.

Drug Mode of Action ::  

(fool-VESS-trant)
Faslodex
Solution for injection
50 mg/mL
Class: Antiestrogen

Drug Interactions ::

 Interactions

None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies. Note history of liver function impairment, bleeding diatheses, thrombocytopenia, or concurrent use of anticoagulants.
  • Ensure that patient has negative pregnancy test before starting therapy.
  • Monitor patient for GI, CNS, general body side effects, and injection site reactions. Inform health care provider if noted and significant.

Drug Storage/Management ::

 Administration/Storage

  • For IM administration only. Not for IV, SC, or ID administration.
  • Administer prescribed dose once monthly using prefilled syringe(s) and supplied safety needle(s).
  • Administer as single 5 mL injection or concurrent 2.5 mL injections into buttock.
  • Administer injection slowly.
  • Do not administer if cloudiness or particulate matter is noted.
  • Store prefilled syringes in refrigerator (36° to 46°C).

Drug Notes ::

 Patient/Family Education

  • Explain name, dose, action, and potential side effects of drug.
  • Advise patient that medication will be prepared and administered by health care provider in a health care setting on a monthly basis.
  • Instruct patient to inform health care provider if any of the following symptoms occur: intolerable nausea, vomiting, constipation, diarrhea, stomach pain, headache, hot flushes, injection site pain or inflammation.
  • Instruct patient to not take any prescription or otc medications or dietary supplements unless advised by health care provider.
  • Instruct women to notify health care provider if they become pregnant, plan on becoming pregnant, or are breastfeeding.
  • Advise patient that follow-up visits and laboratory tests will be required to monitor therapy and to be sure to keep appointments.

Disclaimer ::

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