Details About Generic Salt ::  Glycerin

Main Medicine Class:: Osmotic diuretic Laxative Ophthalmic   

(GLIH-suh-rin)
Colace, Fleet Babylax, Ophthalgan, Osmoglyn, Sani-Supp
Class: Osmotic diuretic Laxative Ophthalmic

 

Drugs Class ::

 Action Reduces intraocular pressure by creating osmotic gradient between plasma and ocular fluids (oral form). Promotes bowel evacuation by local irritation and hyperosmotic actions (rectal form). Reduces edema and clears corneal haze by attracting water through semipermeable corneal epithelium (ophthalmic form).

Indications for Drugs ::

 Indications

Oral: Control of acute attack of glaucoma; reduction of intraocular pressure prior to and after ocular surgery. Rectal: Short-term treatment of constipation; to evacuate the colon for rectal and bowel examinations. Ophthalmic: Clearance of edematous corneas to facilitate ophthalmoscopic and gonioscopic examination in acute glaucoma, bullous keratitis, and Fuchs’ endothelial dystrophy. unlabeled use(s): Reduction of intraocular and intracranial pressure via special IV preparations.

Drug Dose ::

 Route/Dosage

ADULTS: PO 1 to 2 g/kg 1 to 1½ hr prior to surgery. PR Insert 1 suppository (3 g) or 5 to 15 mL as rectal enema and retain 15 min. Topical 1 to 2 gtt instilled in eye(s) prior to examination. CHILDREN > 6 yr: PR Same as adults. CHILDREN 2 to 6 yr: PR 1 to 1.5 g suppository or 2 to 5 mL as rectal enema. CHILDREN < 2 yr: Use only on advice of health care provider.

Contraindication ::

 Contraindications

Oral form: Anuria, severe dehydration, frank or impending acute pulmonary edema, severe cardiac decompensation. Rectal forms: Nausea, vomiting, acute surgical abdomen, fecal impaction, intestinal obstruction, undiagnosed abdominal pain.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Do not administer enemas or suppositories to children < 2 yr. Safety and efficacy of other forms undetermined. Elderly and debilitated patients: Use with caution. Special risk patients: Use oral form with caution in patients with hypovolemia, confused mental states, CHF, diabetes mellitus, and severe dehydration.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CV: Arrhythmias. CNS: Headache; confusion; disorientation; weakness; dizziness; fainting. DERM: Rectal form: Perianal irritation; sweating. EENT: Ophthalmic solution: Ocular pain and irritation. GI: Nausea; vomiting. Rectal form: Excessive bowel activity; abdominal cramps; bloating; flatulence. META: Dehydration; hyperosmolar nonketotic coma.

Drug Mode of Action ::  

 Action Reduces intraocular pressure by creating osmotic gradient between plasma and ocular fluids (oral form). Promotes bowel evacuation by local irritation and hyperosmotic actions (rectal form). Reduces edema and clears corneal haze by attracting water through semipermeable corneal epithelium (ophthalmic form).

Drug Interactions ::

 Interactions None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess for nausea, vomiting, headache, altered neurologic status, and dehydration.
  • With ophthalmic form, assess for eye pain or discomfort.
  • With rectal form, assess last bowel movement, use of laxatives, ability to retain suppository, and effectiveness of drug regimen.
  • Monitor I&O.
  • Systemic administration will cause diuresis and possibly hypotension with dizziness. Institute safety precautions in presence of neurologic manifestations. Have patient maintain supine position after administration.
  • With oral or ophthalmic forms, do not give hypotonic solutions after drug is administered.
  • With rectal form, encourage fluid intake, fiber in diet, and activity.

Drug Storage/Management ::

 Administration/Storage

  • Administer 50% oral solution with 0.9% Sodium Chloride flavored with orange, lemon, or lime juice or administer commercially prepared 50% or 75% flavored solution.
  • Administer suppository high in rectum with patient lying down on side; encourage patient to retain suppository in rectum for at least 15 min.
  • To administer rectal liquid, have patient lie on left side, insert stem of applicator into rectum with tip pointing toward navel, squeeze unit until nearly all liquid has been dispensed, and remove applicator. Small amount of liquid may remain in unit.
  • Ophthalmic solution may cause burning sensation in eye. Local anesthetic should be administered before instillation of drug.
  • Store suppositories in cool location, but do not freeze. Other formulations may be stored at room temperature.

Drug Notes ::

 Patient/Family Education

  • Inform patient of need to maintain supine position after administration of oral form of drug.
  • With rectal form, advise patient about dangers associated with long-term laxative use. Instruct patient in alternative measures to encourage bowel movements (increase fluid intake, increase intake of dietary fiber, increase activity). Instruct patient to avoid laxative use in presence of abdominal pain, vomiting, or nausea.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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