Details About Generic Salt ::  Magaldra

Main Medicine Class:: Antacid   

(MAG-al-drate)

Iosopan, Riopan,  Riopan Extra Strength

Class: Antacid

 

Drugs Class ::

 Action Neutralizes gastric acid, thereby increasing pH of stomach and duodenal bulb. Increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying.

Indications for Drugs ::

 Indications Symptomatic relief of upset stomach associated with hyperacidity, including heartburn, gastroesophageal reflux, acid indigestion and sour stomach; relief of hyperacidity associated with peptic ulcer, gastritis, peptic esophagitis, gastric hyperacidity and hiatal hernia.

Drug Dose ::

 Route/Dosage

ADULTS: PO 480–1080 mg qid prn or to aid in peptic ulcer healing or chronic reflux, give 1 hr and 3 hr after meals and at bedtime (7 doses/day). CHILDREN: PO 5–10 mg/dose q 3–6 hr or 1 hr and 3 hr after meals and at bedtime for peptic ulcer.

Contraindication ::

 Contraindications Severe renal dysfunction; hypophosphatemia; nausea; vomiting; severe abdominal pain; acute surgical abdomen; impaction; intestinal obstruction.

Drug Precautions ::

 Precautions

Pregnancy: Pregnancy category undetermined. Lactation: Undetermined. GI hemorrhage: Use with care in patients with recent massive upper GI hemorrhage. Renal insufficiency: Use with caution in patients with renal impairment to avoid hypermagnesemia and toxicity.

PATIENT CARE CONSIDERATIONS

Drug Side Effects ::

 Adverse Reactions

CNS: Neurotoxicity; encephalopathy. GI: Diarrhea; constipation; intestinal obstruction; rebound hyperacidity. META: Hypophosphatemia; hypermagnesemia. OTHER: Osteomalacia; bone pain; muscular weakness; malaise; decreased fluoride absorption; aluminum accumulation in serum, bone and CNS; milk-alkali syndrome.

Drug Mode of Action ::  

 Action Neutralizes gastric acid, thereby increasing pH of stomach and duodenal bulb. Increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying.

Drug Interactions ::

 Interactions

Iron: Decreased pharmacologic effect of iron. Ketoconazole: Decreased pharmacologic effect of ketoconazole. Nitrofurantoin: Decreased effects of nitrofurantoin. Penicillamine: Decreased pharmacologic effect of penicillamine. Quinidine: Increased pharmacologic effect of quinidine. Quinolones: Decreased pharmacologic effect of quinolones. Salicylates: Decreased pharmacologic effect of salicylates. Sodium polystyrene sulfonate: Concomitant use may cause metabolic alkalosis in patients with renal failure. Tetracyclines: Decreased pharmacologic effect of tetracyclines.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any allergies.
• Assess for heartburn and indigestion, noting location, duration, character and precipitating factors of GI pain.
• Monitor serum magnesium level in patients with renal impairment.
• Monitor level of relief obtained by patient following medication.

OVERDOSAGE: SIGNS & SYMPTOMS   Nausea, vomiting, diarrhea, constipation, hypermagnesemia, hypophosphatemia

Drug Storage/Management ::

 Administration/Storage

• Administer 1 hr and 3 hr after meals and at bedtime when ordered for treatment of ulcers or 4 times/day when ordered as necessary for relief of symptoms.
• If possible, administer antacid 1–2 hr before or after other medications.
• Shake suspension vigorously before pouring. Administer with sufficient water (approximately 4 oz) to ensure that drug reaches stomach.
• Chewable tablet should be chewed thoroughly before swallowing, followed by half a glass of water.
• Store at room temperature.

Drug Notes ::

 Patient/Family Education

• Instruct patient to take medication 1 and 3 hr after meals and at bedtime.
• Warn patient not to take other medications within 2 hr of antacid.
• Review proper use of suspension or tablet form.
• Advise patient to consult physician if problem recurs, if any symptoms that suggest bleeding occur (eg, black tarry stools) or if patient has taken antacids for more than 2 wk.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.