Details About Generic Salt ::  Praziqua

Main Medicine Class:: Anti-infective,Antihelminthic   

(pray-zih-KWAHN-tuhl)

Biltricide

Tablets: 600 mg

Class: Anti-infective/Antihelminthic

 Indications Infections caused by Schistosoma mekongi, S. japonicum, S. mansoni, S. hematobium, liver flukes, Clonorchis sinensis, and Opisthorchis viverrini.

Treatment of neurocysticercosis, tissue flukes (opisthorchis, felineus, Paragonimus westermani, Fasciola hepatica), intestinal flukes (Heterophyes heterophyes, Fascilopsis buski), and intestinal cestodes (Diphyllobothrium latum, Taenia saginata, T. solium, Dipylidium caninum, Hymenolepsis nana), and schistosomiasis (in concurrent use with oxamniquine).

 Contraindications Ocular cysticercosis.

 Route/Dosage

Schistosomiasis

ADULTS and CHILDREN ³ 4 yr: PO 60 mg/kg in 3 equally divided doses q 4 to 6 hr for 1 day.

Clonorchiasis and Opisthorchiasis

ADULTS: PO 75 mg/kg in 3 equally divided doses q 4 to 6 hr for 1 day.

 Interactions

Cimetidine: Plasma levels of praziquantel may be elevated, increasing the pharmacologic and adverse effects.

 Lab Test Interferences None well documented.

 Adverse Reactions

CNS: Malaise; headache; fever; drowsiness; dizziness. DERMATOLOGIC: Urticaria. GI: Abdominal discomfort, with or without nausea. HEPATIC: Increased liver enzymes.

 Precautions

Pregnancy: Category B. Lactation: Excreted in breast milk. Lactating women should avoid breastfeeding on day of treatment and for subsequent 72 hr. Children: Safety and efficacy not established in children < 4 yr.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

• Administer tablets during meals with liquids.
• Instruct patient not to chew tablets.
• Store at room temperature.

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies. Note history of seizures.
• Monitor for side effects, especially malaise, headache, dizziness, abdominal pain, nausea, or fever.

 Patient/Family Education

• Explain that treatment lasts only 1 day for most parasitic infections.
• Instruct patient to take drug with liquids during meals and not to chew tablets.
• Advise patient to have all family members examined for infestation.
• Emphasize need for follow-up examinations.
• Instruct patient to report the following symptoms to health care provider: malaise, headache, dizziness, abdominal pain, nausea, urticaria, or fever.
• Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.

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Drugs Class ::

Indications for Drugs ::

 Indications Infections caused by Schistosoma mekongi, S. japonicum, S. mansoni, S. hematobium, liver flukes, Clonorchis sinensis, and Opisthorchis viverrini.

Treatment of neurocysticercosis, tissue flukes (opisthorchis, felineus, Paragonimus westermani, Fasciola hepatica), intestinal flukes (Heterophyes heterophyes, Fascilopsis buski), and intestinal cestodes (Diphyllobothrium latum, Taenia saginata, T. solium, Dipylidium caninum, Hymenolepsis nana), and schistosomiasis (in concurrent use with oxamniquine).

Drug Dose ::

 Route/Dosage

Schistosomiasis

ADULTS and CHILDREN ³ 4 yr: PO 60 mg/kg in 3 equally divided doses q 4 to 6 hr for 1 day.

Clonorchiasis and Opisthorchiasis

ADULTS: PO 75 mg/kg in 3 equally divided doses q 4 to 6 hr for 1 day.

Contraindication ::

 Contraindications Ocular cysticercosis.

Drug Precautions ::

 Precautions

Pregnancy: Category B. Lactation: Excreted in breast milk. Lactating women should avoid breastfeeding on day of treatment and for subsequent 72 hr. Children: Safety and efficacy not established in children < 4 yr.

Drug Side Effects ::

 Adverse Reactions

CNS: Malaise; headache; fever; drowsiness; dizziness. DERMATOLOGIC: Urticaria. GI: Abdominal discomfort, with or without nausea. HEPATIC: Increased liver enzymes.

Drug Mode of Action ::  

Drug Interactions ::

 Interactions

Cimetidine: Plasma levels of praziquantel may be elevated, increasing the pharmacologic and adverse effects.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies. Note history of seizures.
• Monitor for side effects, especially malaise, headache, dizziness, abdominal pain, nausea, or fever.

Drug Storage/Management ::

 Administration/Storage

• Administer tablets during meals with liquids.
• Instruct patient not to chew tablets.
• Store at room temperature.

Drug Notes ::

 Patient/Family Education

• Explain that treatment lasts only 1 day for most parasitic infections.
• Instruct patient to take drug with liquids during meals and not to chew tablets.
• Advise patient to have all family members examined for infestation.
• Emphasize need for follow-up examinations.
• Instruct patient to report the following symptoms to health care provider: malaise, headache, dizziness, abdominal pain, nausea, urticaria, or fever.
• Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.

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Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.