Details About Generic Salt ::  Triproli

Main Medicine Class::    

(try-PRO-lih-deen HIGH-droe-KLOR-ide)

Zymine

Liquid

1.25 mg/5 mL

Class: Antihistamine, Alkylamine

 

Drugs Class ::

 Action Competitively blocks histamine at H₂ receptor sites.

Indications for Drugs ::

 Indications Symptomatic relief of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis; management of allergic and non-allergic pruritic symptoms, mild uncomplicated urticaria and angioedema.

Drug Dose ::

 Route/Dosage

Adults and Children at least 12 yr: PO 2.5 mg q 4 to 6 hr (max, 10 mg/24 hr).

Children 6 to 12 yr: PO 1.25 mg q 4 to 6 hr (max, 5 mg/24 hr).

Children 4 to 6 yr: PO 0.94 mg q 4 to 6 hr (max, 3.75 mg/24 hr).

Children 2 to 4 yr: PO 0.625 mg q 4 to 6 hr (max, 2.5 mg/24 hr).

Children 4 mo to 2 yr: PO 0.31 mg q 4 to 6 hr (max, 1.25 mg/24 hr).

Contraindication ::

 Contraindications Hypersensitivity to antihistamines; newborn or premature infants; nursing mothers; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO therapy.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Overdosage may cause hallucinations, convulsions, and death. Antihistamines may diminish mental alertness. In young children, triprolidine may produce paradoxical excitation. Elderly: Greater likelihood of dizziness, excessive sedation, syncope, toxic confusional states, and hypotension in patients over 60 yr. Dosage reduction may be required. Special risk patients: Use drug with caution in patients with predisposition to urinary retention, history of bronchial asthma, increased intraocular pressure, hyperthyroidism, sleep apnea, cardiovascular disease, or hypertension. Respiratory disease: Generally not recommended to treat lower respiratory tract symptoms including asthma.

PATIENT CARE CONSIDERATIONS

Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Orthostatic hypotension; palpitations; tachycardia; faintness. CNS: Drowsiness (often transient); sedation; dizziness; faintness; disturbed coordination; excitation.EENT: Blurred vision; nasal stuffiness; dry mouth, nose, and throat; sore throat. GI: Epigastric distress; nausea; vomiting; diarrhea; constipation; change in bowel habits. METABOLIC: Increased appetite, weight gain. RESPIRATORY: Thickening of bronchial secretions. OTHER: Hypersensitivity reactions; photosensitivity.

Drug Mode of Action ::  

 Action Competitively blocks histamine at H₂ receptor sites.

Drug Interactions ::

 Interactions

Alcohol, CNS depressants (eg, narcotics, sedatives): Additive CNS depression possible.

MAO inhibitors: Anticholinergic effects may increase.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies.
• Monitor for potential neurologic side effects especially in elderly and young.
• Obtain CBC if signs of blood dyscrasias are noted.
• Assess LFT results and BUN and serum creatinine as indicated.

OVERDOSAGE: SIGNS & SYMPTOMS   CNS depression, CNS stimulation, hypotension, respiratory depression, coma, seizures

Drug Storage/Management ::

 Administration/Storage

• Give with food.
• Store tablets and oral solution at room temperature in a tight, light-resistant container. Do not freeze oral solution.

Drug Notes ::

 Patient/Family Education

• Explain potential side effects and adverse reactions, and identify problems that should be reported to health care provider.
• Tell patient not to take within 4 days before skin testing procedures.
• Advise patient to take sips of water frequently, suck on ice chips or sugarless hard candy, or chew sugarless chewing gum if dry mouth occurs.
• Instruct patient to avoid alcohol and other CNS depressants.
• Advise patient that drug may cause drowsiness or dizziness and to use caution while driving or performing other tasks requiring mental alertness.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.