Article Contents ::
Details About Generic Salt :: Acebutolol
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM |
| ACEBUTOLOL |
| ß-ADRENERGIC BLOCKER (SELECTIVE) | ANTI-HYPERTENSIVE, ANTI-ARRHYTHMIC |
| also comes under 4B. Anti-Arrhythmics in 4. Cardiovascular System |
| PK: A: Well absorbed D: Extensive M: Hepatic E: Urine, bile, feces & intestine |
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Indications & Dose: HYPERTENSION PO Adult 200-800mg/day in 2 divided doses | VENTRICULAR ARRHYTHMIAS PO Adult Initially 400mg/day in divided doses MD 600-1200mg/day in divided doses max 1.2g/day |
| Contra: Bronchospasm/asthma, COPD, metabolic acidosis, prinzmetal’s angina, cardiogenic shock, hypotension, severe PAD, sinus bradycardia, second/third-degree AV block
Precautions: During drug withdrawal, first-degree AV block, pheochromocytoma ADR: Serious: shortness of breath & dyspnea, worsen cardiac disorders, pneumonitis, HF, heart block, bronchospasm, raynaud’s syndrome, blurred vision, hematological reactions, SLE, Others: nausea, vomiting, diarrhea, rash, coldness of extremities, headache, depression, dizziness, fatigue, myopathy DDI: Serious Glibenclamide/Chlorpropamide leads to hypoglycemia, Methoxyflurane/Cyclopropane/Trichloroethylene leads to myocardial depression Diet: With/without food Monitor: Blood glucose, BP, HR, CNS effects, ECG |