Article Contents ::
Details About Generic Salt :: Albumin
Main Medicine Class:: Hematological System Sub Medicine Class :: Plasma Protein Fractions
5F. PLASMA PROTEIN FRACTIONS in 5. HEMATOLOGICAL SYSTEM |
ALBUMIN |
COLLOID | BLOOD PRODUCT DERIVATIVE |
PK: D: Plasma compartment: 30%-40%, extravascular compartment-67% M: Hepatic E: Intestinal mucosa |
Indications & Dose: HYPOPROTEINEMIA IV Adult 0.5-1g/kg/dose, repeat q1-2 days to replace on going losses | HYPOVOLEMIA IV Adult Initially 25g, may repeat in 15-30min if response is inadequate max 250g within 48h Child 0.5-1g/kg/dose (10-20mL/kg/dose of albumin 5%) max 6g/kg/day |
Contra: Hypersensitivity, anemia, CVD
Precautions: Hepatic impairment, CRF, chronic anemia, low cardiac reserve, normal plasma albumin, hypoproteinemia, enteropathies, pancreatic insufficiency, malnutrition ADR: Serious: CHF precipitation, hypotension, hypervolemia, pulmonary edema, decreased myocardial contractility, anaphylaxis, urticaria, Others: nausea, vomiting, fever, chills, pruritus, headache, rash DDI: Serious Enalapril causes acute hypotension Monitor: BP, pulmonary edema & hemotocrit |