Article Contents ::
- 1 The Brand Name APECEF Has Generic Salt :: Ceftriaxone
- 2 APECEF Is From Company Apex Form. Priced :: Rs. 54
- 3 APECEF have Ceftriaxone is comes under Sub class Cephalosporins of Main Class Anti Infectives
- 4 Main Medicine Class:: Anti Infectives Sub Medicine Class :: Cephalosporins
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
The Brand Name APECEF Has Generic Salt :: Ceftriaxone
APECEF Is From Company Apex Form. Priced :: Rs. 54
APECEF have Ceftriaxone is comes under Sub class Cephalosporins of Main Class Anti Infectives
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Cephalosporins
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Ceftriaxone | INJ | Rs. 54 | V. |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / V. |
| APECEF | Apex Form. | 500MG | V. | Rs. 54 |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From Apex Form. :: APECEF | Ceftriaxone | Anti Infectives | Cephalosporins |
Indications for Drugs ::
Pneumonia, Meningitis, Acute otitis media, Lyme disease, Typhoid fever, Otitis media, Pelvic inflammatory disease, Septicemia, Skin and Skin-Structure Infections, Gonorrhea, Respiratory tract infections, Urinary tract infections, Bone and Joint Infections, Chlamydia infection, Surgical Prophylaxis
Drug Dose ::
Adult: IV Typhoid fever 2 g once daily for 14 days. IV/IM Susceptible infections 1-2 g/day, up to 4 g/day for severe infections. Surgical prophylaxis 1 g as a single dose 0.5-2 hr pre-op. IM Uncomplicated gonorrhoea; Prevention of secondary meningococcal meningitis 250 mg as a single dose. Children under 12 years: The recommended total daily dose is 50 to 75 mg/kg once daily (or twice daily in equally divided doses). In severe infections, up to 80 mg/kg body weight daily may be given. The total daily dose should not exceed 2 gm. In the treatment of meningitis, the initial dose of 100 mg/kg body weight (not to exceed 4 gm daily) once daily (or twice daily in equally divided doses), is recommended. As soon as the causative organism has been identified and its sensitivity, the doses can be reduced accordingly. The usual duration of therapy in meningitis is 7 to 14 days. Renal impairment: CrCl (ml/min) <10 Max: 2 g daily. Contraindication ::
Hypersensitivity to cephalosporins; hyperbilirubinaemic neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hr of ceftriaxone administration due to risk of calcium-ceftriaxone precipitate formation.
Drug Precautions ::
History of penicillin allergy; severe renal impairment; pregnancy and lactation; superinfection.
Drug Side Effects ::
History of penicillin allergy; severe renal impairment; pregnancy and lactation; superinfection.
Pregnancy category ::
2
Drug Mode of Action ::
Ceftriaxone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Drug Interactions ::
May increase nephrotoxicity of aminoglycosides. May diminish therapeutic effect of BCG, typhoid vaccine, Na picosulfate. May increase anticoagulant effect of vit K antagonists (e.g. warfarin). May increase serum level w/ probenecid. Potentially Fatal: Admin w/ Ca-containing IV soln may cause precipitation of a crystalline material in the lungs and kidneys.
