The Brand Name BRIS Has Generic Salt :: Risperidone 

BRIS  Is From Company Biocia Hc. Priced :: Rs. N.I.

BRIS have Risperidone is comes under Sub class Anti Psychotics of  Main Class Nervous System

Main Medicine Class:: Nervous System  Sub Medicine Class :: Anti Psychotics 

Indications for Drugs ::

Acute and chronic psychoses, Mania, Schizophrenia, Bipolar disorder.

Drug Dose ::

Adult: PO: Schizophrenia Initial: 2 mg/day, up to 4 mg/day on the 2nd day if needed. May further adjust doses at wkly intervals. Maintenance: 4-6 mg/day. Max: 16 mg/day. Elderly: Initially, 0.5 mg bid gradually increased in increments of 0.5 mg bid. Maintenance: 1-2 mg bid. Acute manic episodes of bipolar disorder Initial: 2-3 mg once daily. May increase slowly if needed. Max: 6 mg/day. Psychoses: 2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day (Slower titration appropriate in some patients); usual dose range 4-6 mg daily

Contraindication ::

Risperidone is contraindicated in patients with a known hypersensitivity to the product.

Drug Precautions ::

Preexisting CV diseases; discontinue use if signs and symptoms of tardive dyskinesia occur; renal and hepatic impairment, elderly, epilepsy; parkinsonism; pregnancy. May cause drowsiness and orthostatic hypotension. Gradual withdrawal is recommended. Monitor blood glucose in diabetics and patients at risk of developing diabetes.

Drug Side Effects ::

Agitation, anxiety, dizziness, headache, somnolence; orthostatic hypotension; constipation, dyspepsia, nausea, vomiting, abdominal pain, blurred vision, erectile dysfunction, priapism, rhinitis, rash and allergy, galactorrhoea, gynaecomastia, menstrual disorders, extrapyramidal symptoms (rarely). weight gain, oedema, tardive dyskinesia.Potentially Fatal: Neuroleptic malignant syndrome may occur rarely; seizures. May cause increased mortality in elderly with dementia-related psychosis.

Pregnancy category ::

3

Drug Mode of Action ::  

Risperidone is an atypical antipsychotic. Its activity is mediated through a combination of dopamine (D2) and serotonin (5-HT2) receptor antagonism. It also exhibits affinity to adrenergic (?1 and ?2) and histamine (H1) receptors. It is less likely to cause extrapyramidal effects than conventional antipsychotics.

Drug Interactions ::

May antagonise the effects of levodopa and dopamine agonists. May increase serum levels of clozapine when used together. Increased serum levels of carbamazepine when used concurrently. Carbamazepine may also decrease the serum levels of risperidone. Increased risk of neuroleptic malignant syndrome when used with indinavir and ritonavir. Potentially Fatal: Risperidone may enhance the hypotensive effect of certain antihypertensives.