Article Contents ::
Details About Generic Salt :: Calcium Polystyrene Sulfonate
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 21A. TOXICITY AND POISON MANAGEMENT (ANTIDOTES) in 21. TOXICITY AND POISON MANAGEMENT (ANTIDOTES) |
| CALCIUM POLYSTYRENE SULFONATE |
| ANTIDOTE |
| PK: A: None E: Feces (100%) |
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Indications & Dose: HYPERKALEMIA PO Adult 15g TID/QID as a suspension in water/syrup /as a sweetened paste Child 1g/kg/day in divided doses, MD 500mg/kg/day in divided doses | RECTAL Adult Enema: 30g as suspension in 100 mL of 2% methylcellulose 450 & 100 mL of water & retained for 9h Child 1g/kg/day in divided doses, MD 500mg/kg/day in divided doses |
| Contra: Hyperparathyroidism, multiple myeloma, sarcoidosis, metastatic carcinoma with renal failure together with hypercalcemia, oral route of administration in neonates, neonates with reduced gut motility, patient with obstructive bowel disease, magnesium-containing laxatives
Precautions: Rectal use in neonates & children, renal failure ADR: Serious: Severe hypokalemia, hypercalcemia, sodium retention, constipation, Others: diarrhea, anorexia, nausea, vomiting DDI: Serious Tetracyclines (oral) absorption reduces, Antacids causes metabolic acidosis, Sorbitol leads to colonic necrosis Diet: Monitor: Serum electrolytes |