The Brand Name DAPSONE Has Generic Salt :: Dapsone 

DAPSONE  Is From Company Gsk Priced :: Rs. 312.69

DAPSONE have Dapsone is comes under Sub class Anti Leprotics of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Anti Leprotics 

Indications for Drugs ::

Pneumonia, Acne, Leprosy, Dermatitis herpetiformis

Drug Dose ::

Adult: PO Prophylaxis of Pneumocystis (carinii) jiroveci pneumonia50 mg/day (w/ pyrimethamine once wkly). Multibacillary leprosy 100 mg/day (w/ clofazimine and rifampicin in different dosage regimens) for 12 mth. Paucibacillary leprosy 100 mg/day (w/ rifampicin once mthly) for 6 mth. Dermatitis herpetiformis Initial: 50 mg/day, up to 300 mg/day if needed. T

Contraindication ::

Hypersensitivity. Severe anaemia, porphyria.

Drug Precautions ::

G6PD deficiency, methaemoglobin or Hb M. Perform regular blood counts and monitor liver function regularly. Pregnancy and lactation.

Drug Side Effects ::

Anaemia, peripheral neuropathy, haemolysis and methaemoglobinaemia (dose-related), nephrotic syndrome, psychological changes, hepatitis. Others: Nausea, vomiting, anorexia, headache, maculopapular rash, toxic epidermal necrolysis, Stevens-Johnson syndrome. Topical: Dryness, redness, oiliness and peeling at application site. Potentially Fatal: Agranulocytosis, serious cutaneous hypersensitivity reactions, exfoliative dermatitis.

Pregnancy category ::

3

Drug Mode of Action ::  

Dapsone inhibits folic acid synthesis by preventing normal bacterial utilization of PABA (PABA).

Drug Interactions ::

Decreased serum conc of dapsone when used with rifampicin. Increased plasma conc with probenecid, trimethoprim. Antagonize clofazimine.