The Brand Name DISTINON Has Generic Salt :: Pyridostigmine 

DISTINON  Is From Company Samarth Priced :: Rs. 68

DISTINON have Pyridostigmine is comes under Sub class Miscellaneous of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Miscellaneous 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Pyridostigmine  TAB  Rs. 68  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 DISTINON  Samarth  60MG  10 Rs. 68

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Samarth :: DISTINON  Pyridostigmine  Anti Infectives Miscellaneous

Indications for Drugs ::

Reversal of neuromuscular blockade,Myasthenia gravis,Paralytic ileus and post-operative urinary retention

Drug Dose ::

Oral Myasthenia gravis Adult: 0.3-1.2 g daily in divided doses. Child: <6 yr: Initially, 30 mg, 6-12 yr: Initially, 60 mg. Dose may be gradually increased by 15-30 mg on a daily basis until a satisfactory response is observed. Neonatal myasthenia gravis Child: 5-10 mg given every 4-6 hr. Paralytic ileus and postoperative urinary retention Adult: Doses of 60-240 mg. Contraindication ::

GI or urinary obstruction.

Drug Precautions ::

Renal impairment, pregnancy and lactation, epilepsy, bronchial asthma, bradycardia, cardiac arrhythmias, recent coronary occlusion, vagotonia, hyperthyroidism, peptic ulcer, recent bladder/intestinal surgery. Care should be taken in the use of atropine for counteracting side effects.

Drug Side Effects ::

Muscarinic side effects e.g. nausea, vomiting, diarrhoea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis and diaphoresis. Nicotinic side effects include muscle cramps, fasciculation and weakness.

Pregnancy category ::
Pregnancy category


Drug Mode of Action ::  

Pyridostigmine bromide is a potent reversible inhibitor of acetylcholinesterase, the enzyme responsible for destroying acetylcholine. Inhibiting the enzyme allows free transmission of nerve impulses across the neuromuscular junction. Pyridostigmine bromide has a carbonyl ester linkage that is hydrolysed by acetylcholinesterase but much more slowly than is acetylcholine itself.

Drug Interactions ::

Excretion blocked by probenecid.


Disclaimer ::

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