Article Contents ::
Details About Generic Salt :: Dutasteride
Main Medicine Class:: Genito Urinary System Sub Medicine Class :: Drugs For Prostate Disorders
10C. DRUGS FOR PROSTATE DISORDERS in 10. GENITO-URINARY SYSTEM |
DUTASTERIDE |
5ALPHA-REDUCTASE INHIBITOR, SEX HORMONE | DRUGS FOR BPH |
PK: M: Hepatic E: Feces |
Indications & Dose: BENIGN PROSTATIC HYPERPLASIA PO Adult 500µg/day alone (6 months required to assess the benefits of drug) or with tamsulosin |
Contra: Hypersensitivity, women of childbearing potential, children
ADR: Serious: immune system disorder, impotence, Others: decreased libido, ejaculation disorder, breast disorder, dyspepsia, gynecomastia DDI: Serious Ciprofloxacin/Cimetidine/Diltiazem/Ketoconazole/Ritonavir/Verapamil decreases drug clearance & increases its level Diet: With full glass of water Monitor: Fluid intake & output, baseline PSA level, urinary urgency/frequency |