Article Contents ::
- 1 The Brand Name EFZOL Has Generic Salt :: Miconazole
- 2 EFZOL Is From Company Biocin Hc. Priced :: Rs. 24
- 3 EFZOL have Miconazole is comes under Sub class #N/A of Main Class #N/A
- 4 Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
- 5 Disclaimer ::
The Brand Name EFZOL Has Generic Salt :: Miconazole
EFZOL Is From Company Biocin Hc. Priced :: Rs. 24
EFZOL have Miconazole is comes under Sub class #N/A of Main Class #N/A
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Oropharyngeal candidiasis, Oral thrush, Denture stomatitis, Fungal infections of the mouth, Throat and gut, Angular cheilitis, Dermatomycoses, Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor
Drug Dose ::
For oral administration: The usual dose is 15 mg/kg/day in divided doses. Adults : 1-2 tea-spoonfuls of gel 4 times daily. Children aged 6 years and over : 1 tea-spoonful of gel 4 times daily. Children aged 2-6 years : 1 tea-spoonful of gel twice daily1 month – 2 years : 1/2 tea-spoonful of gel twice daily. Localised lesions of mouth:Smear small amount on affected area with clean finger 4 times daily for 5-7 days.
Miconazole Oral Gel is contraindicated in patients with known hypersensitivity to any of its components and in patients with liver dysfunction.
Drug Precautions ::
Caution is required particularly in infants & young children to ensure that the gel does not obstruct the throat.
Drug Side Effects ::
Nausea, vomiting, diarrhoea (with long-term treatment); rarely allergic reactions; isolated reports of hepatitis.
Pregnancy category ::
Drug Mode of Action ::
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Drug Interactions ::
May increase anticoagulant effect of warfarin. May increase or prolong the effect of the following drugs: Oral hypoglycaemics (e.g. sulfonylureas), phenytoin, HIV protease inhibitors (e.g. saquinavir), antineoplastic agents (e.g. vinca alkaloids, busulfan, docetaxel), Ca channel blockers (e.g. dihydropyridines, verapamil), immunosuppressive agents (e.g. ciclosporin, tacrolimus, sirolimus), carbamazepine, cilostazol, buspirone, disopyramide, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine. Potentially Fatal: Increased risk of cardiac arrhythmia w/ astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, terfenadine. May increase exposure to ergot alkaloids leading to ergotism. May increase the risk of rhabdomyolysis w/ HMG-CoA reductase inhibitors (e.g. simvastatin and lovastatin). May increase the effect of triazolam and oral midazolam.